Volume 30, Issue 8 | August 2020

Research
- - LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy
    Susanne Nichterwitz
    Jik Nijssen
    Helena Storvall
    Christoph Schweingruber
    Laura Helen Comley
    Ilary Allodi
    ...[+1 authors]...,
    Mirjam van der Lee
    Qiaolin Deng
    Rickard Sandberg
    Eva Hedlund
    First Published August 20, 2020
  - Diploid genome architecture revealed by multi-omic data of hybrid mice
    Zhijun Han
    Kairong Cui
    Katarzyna Placek
    Ni Hong
    Chengqi Lin
    Wei Chen
    Keji Zhao
    Wenfei Jin
    First Published August 5, 2020
  - ADAR-deficiency perturbs the global splicing landscape in mouse tissues
    Utkarsh Kapoor
    Konstantin Licht
    Fabian Amman
    Tobias Jakobi
    David Martin
    Christoph Dieterich
    Michael F. Jantsch
    First Published July 29, 2020
  - PR-DUB maintains the expression of critical genes through FOXK1/2- and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination
    Petros Kolovos
    Koutarou Nishimura
    Aditya Sankar
    Simone Sidoli
    Paul A. Cloos
    Kristian Helin
    Jesper Christensen
    First Published August 3, 2020
  - Xylem systems genetics analysis reveals a key regulator of lignin biosynthesis in Populus deltoides
    Kelly M. Balmant
    Jerald D. Noble
    Filipe C. Alves
    Christopher Dervinis
    Daniel Conde
    Henry W. Schmidt Ana I. Vazquez
    ...[+2 authors]...,
    William B. Barbazuk
    Gustavo de los Campos
    Marcio F.R. Resende
    Matias Kirst
    First Published August 19, 2020
Methods
- - Detection and characterization of jagged ends of double-stranded DNA in plasma
    Jiang Peiyong
    Xie Tingting
    Ding Spencer C.
    Zhou Ze
    Cheng Suk Hang
    Chan Rebecca W.Y. Lee Wing-Shan Peng Wenlei Wong John Wong Vincent W.S. Chan Henry L.Y. Chan Stephen L. Poon Liona C.Y.
    ...[+8 authors]...,
    Leung Tak Y.
    Chan K.C. Allen
    Chiu Rossa W.K.
    Lo Y.M. Dennis
    First Published August 14, 2020
  - Detection of simple and complex de novo mutations with multiple reference sequences
    Garimella Kiran V.
    Iqbal Zamin
    Krause Michael A.
    Campino Susana
    Kekre Mihir
    Drury Eleanor
    ...[+1 authors]...,
    Kwiatkowski Dominic
    Sá Juliana M.
    Wellems Thomas E.
    McVean Gil
    First Published August 19, 2020
  - A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome
    Fan Gao
    Xuedong Pan
    Elissa B. Dodd-Eaton
    Carlos Vera Recio
    Matthew D. Montierth
    Jasmina Bojadzieva Phuong L. Mai Kristin Zelley Valen E. Johnson Danielle Braun Kim E. Nichols
    ...[+6 authors]...,
    Judy E. Garber
    Sharon A. Savage
    Louise C. Strong
    Wenyi Wang
    First Published August 18, 2020
  - TransBorrow: genome-guided transcriptome assembly by borrowing assemblies from different assemblers
    Ting Yu
    Zengchao Mu
    Zhaoyuan Fang
    Xiaoping Liu
    Xin Gao
    Juntao Liu
    First Published August 17, 2020
  - RNA-Bloom enables reference-free and reference-guided sequence assembly for single-cell transcriptomes
    Ka Ming Nip
    Readman Chiu
    Chen Yang
    Justin Chu
    Hamid Mohamadi
    René L. Warren
    Inanc Birol
    First Published August 17, 2020
  - SNP-based quantitative deconvolution of biological mixtures: application to the detection of cows with subclinical mastitis by whole-genome sequencing of tank milk
    Wouter Coppieters
    Latifa Karim
    Michel Georges
    First Published June 26, 2020
Resource
- - LEMMI: a continuous benchmarking platform for metagenomics classifiers
    Mathieu Seppey
    Mosè Manni
    Evgeny M. Zdobnov
    First Published July 2, 2020

Table of Contents

Volume 30, Issue 8 | August 2020

Research

LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy

Diploid genome architecture revealed by multi-omic data of hybrid mice

ADAR-deficiency perturbs the global splicing landscape in mouse tissues

PR-DUB maintains the expression of critical genes through FOXK1/2- and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination

Xylem systems genetics analysis reveals a key regulator of lignin biosynthesis in Populus deltoides

Methods

Detection and characterization of jagged ends of double-stranded DNA in plasma

Detection of simple and complex de novo mutations with multiple reference sequences

A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome

TransBorrow: genome-guided transcriptome assembly by borrowing assemblies from different assemblers

RNA-Bloom enables reference-free and reference-guided sequence assembly for single-cell transcriptomes

SNP-based quantitative deconvolution of biological mixtures: application to the detection of cows with subclinical mastitis by whole-genome sequencing of tank milk

Resource

LEMMI: a continuous benchmarking platform for metagenomics classifiers

Table of Contents

Volume 30, Issue 8 | August 2020

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Research

Methods

Resource