Volume 28, Issue 5 | May 2018

Editorials
- - Scope note
    First Published April 12, 2018
  - A statement about the publication describing genome sequencing of the Atacama skeleton
    First Published March 30, 2018
Commentary
- - The Atacama skeleton
    Garry Nolan
    Atul Butte
    First Published March 30, 2018
Perspective
- - Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship
    Marie A. Brunet
    Sébastien A. Levesque
    Darel J. Hunting
    Alan A. Cohen
    Xavier Roucou
    First Published April 6, 2018
Research
- - Enduring epigenetic landmarks define the cancer microenvironment
    Ruth Pidsley
    Mitchell G. Lawrence
    Elena Zotenko
    Birunthi Niranjan
    Aaron Statham
    Jenny Song Roman M. Chabanon Wenjia Qu Hong Wang Michelle Richards Shalima S. Nair Nicola J. Armstrong Hieu T. Nim Melissa Papargiris Preetika Balanathan Hugh French Timothy Peters Sam Norden Andrew Ryan John Pedersen James Kench Roger J. Daly Lisa G. Horvath Phillip Stricker Mark Frydenberg
    ...[+20 authors]...,
    Renea A. Taylor
    Clare Stirzaker
    Gail P. Risbridger
    Susan J. Clark
    First Published April 12, 2018
  - L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis
    Stephanie N. Schauer
    Patricia E. Carreira
    Ruchi Shukla
    Daniel J. Gerhardt
    Patricia Gerdes
    Francisco J. Sanchez-Luque Paola Nicoli Michaela Kindlova Serena Ghisletti Alexandre Dos Santos Delphine Rapoud Didier Samuel
    ...[+7 authors]...,
    Jamila Faivre
    Adam D. Ewing
    Sandra R. Richardson
    Geoffrey J. Faulkner
    First Published April 11, 2018
  - In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
    Arnoud Boot
    Mi Ni Huang
    Alvin W.T. Ng
    Szu-Chi Ho
    Jing Quan Lim
    Yoshiiku Kawakami
    ...[+1 authors]...,
    Kazuaki Chayama
    Bin Tean Teh
    Hidewaki Nakagawa
    Steven G. Rozen
    First Published April 9, 2018
  - Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers
    Bettina Meier
    Nadezda V. Volkova
    Ye Hong
    Pieta Schofield
    Peter J. Campbell
    First Published April 10, 2018
  - Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome
    Cai Li
    Boris Lenhard
    Nicholas M. Luscombe
    First Published April 4, 2018
  - HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo
    Jonathan M. Howard
    Hai Lin
    Andrew J. Wallace
    Garam Kim
    Jolene M. Draper
    Maximilian Haeussler
    ...[+1 authors]...,
    Sol Katzman
    Masoud Toloue
    Yunlong Liu
    Jeremy R. Sanford
    First Published April 12, 2018
  - In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors
    F.X. Reymond Sutandy
    Stefanie Ebersberger
    Lu Huang
    Anke Busch
    Maximilian Bach
    Hyun-Seo Kang Jörg Fallmann Daniel Maticzka Rolf Backofen Peter F. Stadler
    ...[+5 authors]...,
    Kathi Zarnack
    Michael Sattler
    Stefan Legewie
    Julian König
    First Published April 11, 2018
Methods
- - Double insertion of transposable elements provides a substrate for the evolution of satellite DNA
    Michael P. McGurk
    Daniel A. Barbash
    First Published March 27, 2018
  - Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer
    Eva K.F. Chan
    Daniel L. Cameron
    Desiree C. Petersen
    Ruth J. Lyons
    Benedetta F. Baldi
    First Published April 4, 2018
  - Sequential regulatory activity prediction across chromosomes with convolutional neural networks
    David R. Kelley
    Yakir A. Reshef
    Maxwell Bileschi
    David Belanger
    Cory Y. McLean
    First Published March 27, 2018
  - taxMaps: comprehensive and highly accurate taxonomic classification of short-read data in reasonable time
    André Corvelo
    Wayne E. Clarke
    Nicolas Robine
    Michael C. Zody
    First Published March 27, 2018
Resource
- - Hackathons as a means of accelerating scientific discoveries and knowledge transfer
    Amel Ghouila
    Geoffrey Henry Siwo
    Jean-Baka Domelevo Entfellner
    Sumir Panji
    Katrina A. Button-Simons
    Sage Zenon Davis Faisal M. Fadlelmola Michael T. Ferdig Nicola Mulder Taoufik Bensellak Anita Ghansah Kais Ghedira Ashley Gritzman Itunuoluwa Isewon Ali Kishk Ahmed Moussa Cheikh Loucoubar Patrick Musicha Meenal Pore
    ...[+14 authors]...,
    David Moinina Sengeh
    Darlington Shingirirai Mapiye
    Pavan Kumar Rallabandi
    Melvin Varughese
    First Published April 12, 2018
Corrigenda
- - Corrigendum: Detecting differential copy number variation between groups of samples
    Craig B. Lowe
    Nicelio Sanchez-Luege
    Timothy R. Howes
    Shannon D. Brady
    Rhea R. Daugherty
    First Published May 1, 2018
  - Corrigendum: Evolutionary expansion of DNA hypomethylation in the mammalian germline genome
    Jianghan Qu
    Emily Hodges
    Antoine Molaro
    Pascal Gagneux
    Matthew D. Dean
    First Published May 1, 2018
  - Corrigendum: A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity
    Fumitaka Inoue
    Martin Kircher
    Beth Martin
    Gregory M. Cooper
    Daniela M. Witten
    First Published May 1, 2018

Table of Contents

Volume 28, Issue 5 | May 2018

Editorials

Scope note

A statement about the publication describing genome sequencing of the Atacama skeleton

Commentary

The Atacama skeleton

Perspective

Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship

Research

Enduring epigenetic landmarks define the cancer microenvironment

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis

In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors

Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers

Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome

HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo

In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors

Methods

Double insertion of transposable elements provides a substrate for the evolution of satellite DNA

Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer

Sequential regulatory activity prediction across chromosomes with convolutional neural networks

taxMaps: comprehensive and highly accurate taxonomic classification of short-read data in reasonable time

Resource

Hackathons as a means of accelerating scientific discoveries and knowledge transfer

Corrigenda

Corrigendum: Detecting differential copy number variation between groups of samples

Corrigendum: Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

Corrigendum: A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity

Table of Contents

Volume 28, Issue 5 | May 2018

Share this issue

Editorials

Commentary

Perspective

Research

Methods

Resource

Corrigenda