Volume 28, Issue 1 | January 2018

Research
- - Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection
    Konstantin Popadin
    Stephan Peischl
    Marco Garieri
    M. Reza Sailani
    Audrey Letourneau
    Federico Santoni Samuel W. Lukowski Georgii A. Bazykin Sergey Nikolaev
    ...[+4 authors]...,
    Diogo Meyer
    Laurent Excoffier
    Alexandre Reymond
    Stylianos E. Antonarakis
    First Published December 13, 2017
  - Saturation mutagenesis reveals manifold determinants of exon definition
    Shengdong Ke
    Vincent Anquetil
    Jorge Rojas Zamalloa
    Alisha Maity
    Anthony Yang
    Mauricio A. Arias
    ...[+1 authors]...,
    Sergey Kalachikov
    James J. Russo
    Jingyue Ju
    Lawrence A. Chasin
    First Published December 14, 2017
  - Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini
    Chan Hyun Na
    Mustafa A. Barbhuiya
    Min-Sik Kim
    Steven Verbruggen
    Stephen M. Eacker
    Olga Pletnikova Juan C. Troncoso
    ...[+2 authors]...,
    Marc K. Halushka
    Gerben Menschaert
    Christopher M. Overall
    Akhilesh Pandey
    First Published November 21, 2017
  - H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2
    Carol C.L. Chen
    Preeti Goyal
    Mohammad M. Karimi
    Marie H. Abildgaard
    Hiroshi Kimura
    First Published December 11, 2017
  - Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus
    Jaaved Mohammed
    Alex S. Flynt
    Alexandra M. Panzarino
    Md Mosharrof Hossain Mondal
    Matthew DeCruz
    First Published December 12, 2017
  - DNA mismatch repair preferentially protects genes from mutation
    Eric J. Belfield
    Zhong Jie Ding
    Fiona J.C. Jamieson
    Anne M. Visscher
    Shao Jian Zheng
    First Published December 12, 2017
Methods
- - SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells
    Kyung Yeon Han
    Kyu-Tae Kim
    Je-Gun Joung
    Dae-Soon Son
    Yeon Jeong Kim
    Areum Jo Hyo-Jeong Jeon Hui-Sung Moon Chang Eun Yoo Woosung Chung Hye Hyeon Eum Sangmin Kim Hong Kwan Kim Jeong Eon Lee
    ...[+9 authors]...,
    Myung-Ju Ahn
    Hae-Ock Lee
    Donghyun Park
    Woong-Yang Park
    First Published December 5, 2017
  - Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI
    Ruben Boers
    Joachim Boers
    Bas de Hoon
    Christel Kockx
    Zeliha Ozgur
    First Published December 8, 2017
  - ABCA4 midigenes reveal the full splice spectrum of all reported noncanonical splice site variants in Stargardt disease
    Riccardo Sangermano
    Mubeen Khan
    Stéphanie S. Cornelis
    Valerie Richelle
    Silvia Albert
    Alejandro Garanto Duaa Elmelik Raheel Qamar
    ...[+3 authors]...,
    Dorien Lugtenberg
    L. Ingeborgh van den Born
    Rob W.J. Collin
    Frans P.M. Cremers
    First Published November 21, 2017
  - SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site
    Liyang Zhang
    Gabriella D. Martini
    H. Tomas Rube
    Judith F. Kribelbauer
    Chaitanya Rastogi
    First Published December 1, 2017
Resources
- - Impact of regulatory variation across human iPSCs and differentiated cells
    Nicholas E. Banovich
    Yang I. Li
    Anil Raj
    Michelle C. Ward
    Peyton Greenside
    Diego Calderon Po Yuan Tung Jonathan E. Burnett Marsha Myrthil Samantha M. Thomas Courtney K. Burrows Irene Gallego Romero
    ...[+7 authors]...,
    Bryan J. Pavlovic
    Anshul Kundaje
    Jonathan K. Pritchard
    Yoav Gilad
    First Published December 5, 2017
  - The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting
    Lishi Li
    Yulong Song
    Xinrui Shi
    Jianheng Liu
    Shaolei Xiong
    Wanying Chen
    ...[+1 authors]...,
    Qiang Fu
    Zichao Huang
    Nannan Gu
    Rui Zhang
    First Published December 12, 2017
Corrigendum
- - Corrigendum: Discovery and genotyping of structural variation from long-read haploid genome sequence data
    John Huddleston
    Mark J.P. Chaisson
    Karyn Meltz Steinberg
    Wes Warren
    Kendra Hoekzema
    David Gordon Tina A. Graves-Lindsay Katherine M. Munson Zev N. Kronenberg Laura Vives Paul Peluso Matthew Boitano
    ...[+7 authors]...,
    Chen-Shin Chin
    Jonas Korlach
    Richard K. Wilson
    Evan E. Eichler
    First Published January 2, 2018

Table of Contents

Volume 28, Issue 1 | January 2018

Research

Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection

Saturation mutagenesis reveals manifold determinants of exon definition

Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2

Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus

DNA mismatch repair preferentially protects genes from mutation

Methods

SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells

Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

ABCA4 midigenes reveal the full splice spectrum of all reported noncanonical splice site variants in Stargardt disease

SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site

Resources

Impact of regulatory variation across human iPSCs and differentiated cells

The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting

Corrigendum

Corrigendum: Discovery and genotyping of structural variation from long-read haploid genome sequence data

Table of Contents

Volume 28, Issue 1 | January 2018

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Research

Methods

Resources

Corrigendum