Volume 24, Issue 5 | May 2014

Perspective
- - Can I be sued for that? Liability risk and the disclosure of clinically significant genetic research findings
    Amy L. McGuire
    Bartha Maria Knoppers
    Ma’n H. Zawati
    Ellen Wright Clayton
    First Published March 27, 2014
Research
- - PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration
    Christopher L. Baker
    Michael Walker
    Shimpei Kajita
    Petko M. Petkov
    Kenneth Paigen
    First Published March 6, 2014
  - Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis
    Henne Holstege
    Wayne Pfeiffer
    Daoud Sie
    Marc Hulsman
    Thomas J. Nicholas
    Clarence C. Lee Tristen Ross Jue Lin Mark A. Miller Bauke Ylstra Hanne Meijers-Heijboer Martijn H. Brugman Frank J.T. Staal Gert Holstege
    ...[+9 authors]...,
    Marcel J.T. Reinders
    Timothy T. Harkins
    Samuel Levy
    Erik A. Sistermans
    First Published April 23, 2014
  - Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival
    Scott D. Brown
    Rene L. Warren
    Ewan A. Gibb
    Spencer D. Martin
    John J. Spinelli
    First Published April 29, 2014
  - Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition
    Dan E. Webster
    Brook Barajas
    Rose T. Bussat
    Karen J. Yan
    Poornima H. Neela
    First Published January 17, 2014
  - Recurrent epimutations activate gene body promoters in primary glioblastoma
    Raman P. Nagarajan
    Bo Zhang
    Robert J.A. Bell
    Brett E. Johnson
    Adam B. Olshen
    Vasavi Sundaram Daofeng Li Ashley E. Graham Aaron Diaz Shaun D. Fouse Ivan Smirnov
    ...[+6 authors]...,
    Jun Song
    Pamela L. Paris
    Ting Wang
    Joseph F. Costello
    First Published April 7, 2014
  - Identifying mRNA sequence elements for target recognition by human Argonaute proteins
    Jingjing Li
    TaeHyung Kim
    Razvan Nutiu
    Debashish Ray
    Timothy R. Hughes
    First Published March 24, 2014
  - Evolution of splicing regulatory networks in Drosophila
    C. Joel McManus
    Joseph D. Coolon
    Jodi Eipper-Mains
    Patricia J. Wittkopp
    Brenton R. Graveley
    First Published February 10, 2014
  - Tempo and mode of regulatory evolution in Drosophila
    Joseph D. Coolon
    C. Joel McManus
    Kraig R. Stevenson
    Brenton R. Graveley
    Patricia J. Wittkopp
    First Published February 24, 2014
  - High-resolution mapping defines the cooperative architecture of Polycomb response elements
    Guillermo A. Orsi
    Sivakanthan Kasinathan
    Kelly T. Hughes
    Sarah Saminadin-Peter
    Steven Henikoff
    First Published March 25, 2014
  - Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity
    Sachiko Takayama
    Joseph Dhahbi
    Adam Roberts
    Guanxiong Mao
    Seok-Jin Heo
    First Published February 20, 2014
  - Widespread and frequent horizontal transfers of transposable elements in plants
    Moaine El Baidouri
    Marie-Christine Carpentier
    Richard Cooke
    Dongying Gao
    Eric Lasserre
    Christel Llauro
    ...[+1 authors]...,
    Marie Mirouze
    Nathalie Picault
    Scott A. Jackson
    Olivier Panaud
    First Published February 11, 2014
  - Predicting the virulence of MRSA from its genome sequence
    Maisem Laabei
    Mario Recker
    Justine K. Rudkin
    Mona Aldeljawi
    Zeynep Gulay
    Tim J. Sloan Paul Williams Jennifer L. Endres Kenneth W. Bayles Paul D. Fey Vijaya Kumar Yajjala Todd Widhelm Erica Hawkins Katie Lewis Sara Parfett Lucy Scowen Sharon J. Peacock Matthew Holden Daniel Wilson Timothy D. Read Jean van den Elsen Nicholas K. Priest
    ...[+17 authors]...,
    Edward J. Feil
    Laurence D. Hurst
    Elisabet Josefsson
    Ruth C. Massey
    First Published April 9, 2014
  - A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection
    Katherine J. Siddle
    Matthieu Deschamps
    Ludovic Tailleux
    Yohann Nédélec
    Julien Pothlichet
    Geanncarlo Lugo-Villarino Valentina Libri Brigitte Gicquel Olivier Neyrolles
    ...[+4 authors]...,
    Guillaume Laval
    Etienne Patin
    Luis B. Barreiro
    Lluís Quintana-Murci
    First Published January 30, 2014
Methods
- - General approach for in vivo recovery of cell type-specific effector gene sets
    Julius C. Barsi
    Qiang Tu
    Eric H. Davidson
    First Published March 6, 2014
  - ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs
    Piotr J. Balwierz
    Mikhail Pachkov
    Phil Arnold
    Andreas J. Gruber
    Mihaela Zavolan
    First Published February 10, 2014

Table of Contents

Volume 24, Issue 5 | May 2014

Perspective

Can I be sued for that? Liability risk and the disclosure of clinically significant genetic research findings

Research

PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration

Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition

Recurrent epimutations activate gene body promoters in primary glioblastoma

Identifying mRNA sequence elements for target recognition by human Argonaute proteins

Evolution of splicing regulatory networks in Drosophila

Tempo and mode of regulatory evolution in Drosophila

High-resolution mapping defines the cooperative architecture of Polycomb response elements

Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity

Widespread and frequent horizontal transfers of transposable elements in plants

Predicting the virulence of MRSA from its genome sequence

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

Methods

General approach for in vivo recovery of cell type-specific effector gene sets

ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs

Table of Contents

Volume 24, Issue 5 | May 2014

Share this issue

Perspective

Research

Methods