
Cover Double-Nobel Prize winner Frederick Sanger (1918–2013) rendered as a mosaic of DNA sequencing gel autoradiographs used in the original Sanger technique. In this issue, a tribute in memory of Fred is shared by Bruce Roe who spent his 1978–1979 sabbatical helping to develop the method in Fred’s lab. (Photomosaic by Victor O. Leshyk [www.victorleshyk.com] using a hand-drawn illustration and AndreaMosaic software, and based on an original photo of Fred Sanger provided courtesy of the MRC Laboratory of Molecular Biology. [For tribute, see pp. xi–xii.])