Volume 18, Issue 8 | August 2008

PERSPECTIVES
- - Genomic medicine in Mexico: Initial steps and the road ahead
    Gerardo Jimenez-Sanchez
    Irma Silva-Zolezzi
    Alfredo Hidalgo
    Santiago March
    First Published August 1, 2008
  - The opossum genome: Insights and opportunities from an alternative mammal
    Paul B. Samollow
    First Published August 1, 2008
LETTERS
- - Transcription induces strand-specific mutations at the 5′ end of human genes
    Paz Polak
    Peter F. Arndt
    First Published May 7, 2008
  - A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation
    Zheng Lian
    Alexander Karpikov
    Jin Lian
    Milind C. Mahajan
    Stephen Hartman
    First Published May 16, 2008
  - Detection and characterization of silencers and enhancer-blockers in the greater CFTR locus
    Hanna M. Petrykowska
    Christopher M. Vockley
    Laura Elnitski
    First Published April 24, 2008
  - A systematic analysis of intronic sequences downstream of 5′ splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation
    Isabel Aznarez
    Yoseph Barash
    Ofer Shai
    David He
    Julian Zielenski
    Lap-Chee Tsui
    ...[+1 authors]...,
    John Parkinson
    Brendan J. Frey
    Johanna M. Rommens
    Benjamin J. Blencowe
    First Published May 2, 2008
  - DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts
    Brian P. Chadwick
    First Published May 2, 2008
  - Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing
    David Monk
    Alexandre Wagschal
    Philippe Arnaud
    Pari-Sima Müller
    Layla Parker-Katiraee
    Déborah Bourc’his
    ...[+1 authors]...,
    Stephen W. Scherer
    Robert Feil
    Philip Stanier
    Gudrun E. Moore
    First Published May 14, 2008
  - A gene duplication affecting expression of the ovine ASIP gene is responsible for white and black sheep
    Belinda J. Norris
    Vicki A. Whan
    First Published May 20, 2008
  - Revisiting the Saccharomyces cerevisiae predicted ORFeome
    Qian-Ru Li
    Anne-Ruxandra Carvunis
    Haiyuan Yu
    Jing-Dong J. Han
    Quan Zhong
    Nicolas Simonis Stanley Tam Tong Hao Niels J. Klitgord Denis Dupuy Danny Mou Ilan Wapinski
    ...[+7 authors]...,
    Aviv Regev
    David E. Hill
    Michael E. Cusick
    Marc Vidal
    First Published May 23, 2008
Methods
- - Confounding between recombination and selection, and the Ped/Pop method for detecting selection
    Paul F. O’Reilly
    Ewan Birney
    David J. Balding
    First Published July 10, 2008
  - Inferring causal relationships among different histone modifications and gene expression
    Hong Yu
    Shanshan Zhu
    Bing Zhou
    Huiling Xue
    Jing-Dong J. Han
    First Published June 18, 2008
  - Cross-species de novo identification of cis-regulatory modules with GibbsModule: Application to gene regulation in embryonic stem cells
    Dan Xie
    Jun Cai
    Na-Yu Chia
    Huck H. Ng
    Sheng Zhong
    First Published May 15, 2008
  - An MCMC algorithm for haplotype assembly from whole-genome sequence data
    Vikas Bansal
    Aaron L. Halpern
    Nelson Axelrod
    Vineet Bafna
    First Published August 1, 2008
  - Identification of ancient remains through genomic sequencing
    Matthew J. Blow
    Tao Zhang
    Tanja Woyke
    Camilla F. Speller
    Andrei Krivoshapkin
    First Published April 21, 2008
RESOURCES
- - A novel DNA sequence database for analyzing human demographic history
    Jeffrey D. Wall
    Murray P. Cox
    Fernando L. Mendez
    August Woerner
    Tesa Severson
    First Published May 20, 2008
  - DupMasker: A tool for annotating primate segmental duplications
    Zhaoshi Jiang
    Robert Hubley
    Arian Smit
    Evan E. Eichler
    First Published May 23, 2008
  - The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution
    Matthew M. Hill
    Karl W. Broman
    Elia Stupka
    William C. Smith
    Di Jiang
    First Published June 2, 2008
ERRATUM
- - Errata
    First Published August 1, 2008

Table of Contents

Volume 18, Issue 8 | August 2008

PERSPECTIVES

Genomic medicine in Mexico: Initial steps and the road ahead

The opossum genome: Insights and opportunities from an alternative mammal

LETTERS

Transcription induces strand-specific mutations at the 5′ end of human genes

A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3′ end RNA polyadenylation

Detection and characterization of silencers and enhancer-blockers in the greater CFTR locus

A systematic analysis of intronic sequences downstream of 5′ splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation

DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts

Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing

A gene duplication affecting expression of the ovine ASIP gene is responsible for white and black sheep

Revisiting the Saccharomyces cerevisiae predicted ORFeome

Methods

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

Inferring causal relationships among different histone modifications and gene expression

Cross-species de novo identification of cis-regulatory modules with GibbsModule: Application to gene regulation in embryonic stem cells

An MCMC algorithm for haplotype assembly from whole-genome sequence data

Identification of ancient remains through genomic sequencing

RESOURCES

A novel DNA sequence database for analyzing human demographic history

DupMasker: A tool for annotating primate segmental duplications

The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution

ERRATUM

Errata

Table of Contents

Volume 18, Issue 8 | August 2008

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PERSPECTIVES

LETTERS

Methods

RESOURCES

ERRATUM