Volume 12, Issue 4 | April 2002

INSIGHT/OUTLOOK
- - New Twists on the Epigenetics of CpG Islands
    Rolf Ohlsson
    Chandrasekhar Kanduri
    First Published April 1, 2002
  - Functional Diversity of Mx Proteins: Variations on a Theme of Host Resistance to Infection
    Seung-Hwan Lee
    Silvia M. Vidal
    First Published April 1, 2002
ARTICLES
- - The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity
    James E. Galagan
    Chad Nusbaum
    Alice Roy
    Matthew G. Endrizzi
    Pendexter Macdonald
    Will FitzHugh Sarah Calvo Reinhard Engels Serge Smirnov Deven Atnoor Adam Brown Nicole Allen Jerome Naylor Nicole Stange-Thomann Kurt DeArellano Robin Johnson Lauren Linton Paul McEwan Kevin McKernan Jessica Talamas Andrea Tirrell Wenjuan Ye Andrew Zimmer Robert D. Barber Isaac Cann David E. Graham David A. Grahame Adam M. Guss Reiner Hedderich Cheryl Ingram-Smith H. Craig Kuettner Joseph A. Krzycki John A. Leigh Weixi Li Jinfeng Liu Biswarup Mukhopadhyay John N. Reeve Kerry Smith Timothy A. Springer Lowell A. Umayam Owen White Robert H. White Everly Conway de Macario James G. Ferry Ken F. Jarrell Hua Jing Alberto J.L. Macario Ian Paulsen Matthew Pritchett Kevin R. Sowers Ronald V. Swanson
    ...[+46 authors]...,
    Steven H. Zinder
    Eric Lander
    William W. Metcalf
    Bruce Birren
    First Published April 1, 2002
  - A Genome-Wide Screen for Normally Methylated Human CpG Islands That Can Identify Novel Imprinted Genes
    Liora Z. Strichman-Almashanu
    Richard S. Lee
    Patrick O. Onyango
    Elizabeth Perlman
    Folke Flam
    First Published March 20, 2002
LETTERS
- - Annotated Expressed Sequence Tags and cDNA Microarrays for Studies of Brain and Behavior in the Honey Bee
    Charles W. Whitfield
    Mark R. Band
    Maria F. Bonaldo
    Charu G. Kumar
    Lei Liu
    First Published April 1, 2002
  - Comparative Analysis of Chloroplast Genomes: Functional Annotation, Genome-Based Phylogeny, and Deduced Evolutionary Patterns
    Javier De Las Rivas
    Juan Jose Lozano
    Angel R. Ortiz
    First Published April 1, 2002
  - Functional Genomics on Potato Virus A: Virus Genome-Wide Map of Sites Essential for Virus Propagation
    Tuija Kekarainen
    Harri Savilahti
    Jari P.T. Valkonen
    First Published March 20, 2002
  - Polymorphisms and the Differential Antiviral Activity of the Chicken Mx Gene
    Jae-Hong Ko
    Hee-Kyung Jin
    Atsushi Asano
    Ayato Takada
    Ai Ninomiya
    Hiroshi Kida Hironao Hokiyama Mutsuo Ohara
    ...[+3 authors]...,
    Masaoki Tsuzuki
    Masahide Nishibori
    Makoto Mizutani
    Tomomasa Watanabe
    First Published March 20, 2002
  - Patterns of Human Diversity, within and among Continents, Inferred from Biallelic DNA Polymorphisms
    Chiara Romualdi
    David Balding
    Ivane S. Nasidze
    Gregory Risch
    Myles Robichaux
    First Published April 1, 2002
  - Vestibular Dysfunction in the Epistatic circler Mouse Is Caused by Phenotypic Interaction of One Recessive Gene and Three Modifier Genes
    Kim Cryns
    Michiel P. Van Spaendonck
    Kris Flothmann
    Arjan M. van Alphen
    Paul H. Van De Heyning
    First Published March 20, 2002
  - A Quantitative Trait Locus Influencing Anxiety in the Laboratory Rat
    Alberto Fernández-Teruel
    Rosa M. Escorihuela
    Jeffrey A. Gray
    Raúl Aguilar
    Luis Gil
    Lydia Giménez-Llort Adolf Tobeña Amarjit Bhomra Alison Nicod
    ...[+4 authors]...,
    Richard Mott
    Peter Driscoll
    Gerard R. Dawson
    Jonathan Flint
    First Published March 20, 2002
  - Complex SNP-Based Haplotypes in Three Human Helicases: Implications for Cancer Association Studies
    Dimitra Trikka
    Zhe Fang
    Alex Renwick
    Sally H. Jones
    Ranajit Chakraborty
    First Published April 1, 2002
  - Engineering a Reduced Escherichia coli Genome
    Vitaliy Kolisnychenko
    Guy Plunkett
    Christopher D. Herring
    Tamás Fehér
    János Pósfai
    First Published April 1, 2002
METHODS
- - Predicting Gene Ontology Functions from ProDom and CDD Protein Domains
    Jonathan Schug
    Sharon Diskin
    Joan Mazzarelli
    Brian P. Brunk
    Christian J. Stoeckert
    First Published April 1, 2002
RESOURCE
- - BLAT—The BLAST-Like Alignment Tool
    W. James Kent
    First Published March 20, 2002

Table of Contents

Volume 12, Issue 4 | April 2002

INSIGHT/OUTLOOK

New Twists on the Epigenetics of CpG Islands

Functional Diversity of Mx Proteins: Variations on a Theme of Host Resistance to Infection

ARTICLES

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

A Genome-Wide Screen for Normally Methylated Human CpG Islands That Can Identify Novel Imprinted Genes

LETTERS

Annotated Expressed Sequence Tags and cDNA Microarrays for Studies of Brain and Behavior in the Honey Bee

Comparative Analysis of Chloroplast Genomes: Functional Annotation, Genome-Based Phylogeny, and Deduced Evolutionary Patterns

Functional Genomics on Potato Virus A: Virus Genome-Wide Map of Sites Essential for Virus Propagation

Polymorphisms and the Differential Antiviral Activity of the Chicken Mx Gene

Patterns of Human Diversity, within and among Continents, Inferred from Biallelic DNA Polymorphisms

Vestibular Dysfunction in the Epistatic circler Mouse Is Caused by Phenotypic Interaction of One Recessive Gene and Three Modifier Genes

A Quantitative Trait Locus Influencing Anxiety in the Laboratory Rat

Complex SNP-Based Haplotypes in Three Human Helicases: Implications for Cancer Association Studies

Engineering a Reduced Escherichia coli Genome

METHODS

Predicting Gene Ontology Functions from ProDom and CDD Protein Domains

RESOURCE

BLAT—The BLAST-Like Alignment Tool

Table of Contents

Volume 12, Issue 4 | April 2002

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INSIGHT/OUTLOOK

ARTICLES

LETTERS

METHODS

RESOURCE