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Research

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

  • First Published October 29, 2010
Research

Pervasive gene content variation and copy number variation in maize and its undomesticated progenitor

  • First Published October 29, 2010
Research

Caenorhabditis elegans" > Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegans

  • First Published October 29, 2010
Resource

Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans

  • First Published October 27, 2010
Method

Caenorhabditis nematode genome with RNA-seq" > Scaffolding a Caenorhabditis nematode genome with RNA-seq

  • First Published October 27, 2010
Resource

Dindel: Accurate indel calls from short-read data

  • First Published October 27, 2010
Resource

Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads

  • First Published October 27, 2010
Resource

SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples

  • First Published October 27, 2010
Research

Adaptive selection of an incretin gene in Eurasian populations

  • First Published October 26, 2010
Research

Extensive recombination rate variation in the house mouse species complex inferred from genetic linkage maps

  • First Published October 26, 2010
Research

trans and cis mutations" > Coevolution within a transcriptional network by compensatory trans and cis mutations

  • First Published October 26, 2010
Research

Localized hypermutation and associated gene losses in legume chloroplast genomes

  • First Published October 26, 2010
Research

OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution

  • First Published October 25, 2010
Method

Next-generation sequencing identifies the natural killer cell microRNA transcriptome

  • First Published October 8, 2010
Research

Radiation pharmacogenomics: A genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines

  • First Published October 5, 2010
Research

Drosophila and mammals" > Conservation of an RNA regulatory map between Drosophila and mammals

  • First Published October 4, 2010
Research

Young proteins experience more variable selection pressures than old proteins

  • First Published October 4, 2010
Research

Ancestral grass karyotype reconstruction unravels new mechanisms of genome shuffling as a source of plant evolution

  • First Published September 28, 2010
Research

RNA synthesis precision is regulated by preinitiation complex turnover

  • First Published September 20, 2010
Research

Overlapping codes within protein-coding sequences

  • First Published September 14, 2010
Research

A unique H3K4me2 profile marks tissue-specific gene regulation

  • First Published September 14, 2010
Research

De novo rates and selection of large copy number variation

  • First Published September 14, 2010
Method

Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes

  • First Published September 14, 2010
Research

Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites" > Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites

  • First Published September 9, 2010
Research

Shifts in the intensity of purifying selection: An analysis of genome-wide polymorphism data from two closely related yeast species

  • First Published September 4, 2010
Research

Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

  • First Published September 1, 2010
Method

Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing

  • First Published September 1, 2010
Resource

Candida albicans using RNA-seq" > Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq

  • First Published September 1, 2010
Resource

Detecting copy number variation with mated short reads

  • First Published August 30, 2010
Method

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

  • First Published August 27, 2010
Research

Drosophila" > Age-dependent chromosomal distribution of male-biased genes in Drosophila

  • First Published August 26, 2010
Research

A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution

  • First Published August 24, 2010
Research

Reshaping the gut microbiome with bacterial transplantation and antibiotic intake

  • First Published August 24, 2010
Research

A comprehensive survey of 3′ animal miRNA modification events and a possible role for 3′ adenylation in modulating miRNA targeting effectiveness

  • First Published August 18, 2010
Research

p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy

  • First Published August 17, 2010
Research

Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer

  • First Published August 17, 2010
Research

Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis

  • First Published August 13, 2010
Research

cis-regulatory architecture of mouse photoreceptors" > CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors

  • First Published August 6, 2010
Method

Optimization of de novo transcriptome assembly from next-generation sequencing data

  • First Published August 6, 2010
Research

Massive turnover of functional sequence in human and other mammalian genomes

  • First Published August 6, 2010
Research

Signatures of positive selection apparent in a small sample of human exomes

  • First Published August 6, 2010
Research

CACNG2" > Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2

  • First Published August 5, 2010
Research

Genomic signatures of germline gene expression

  • First Published August 4, 2010
Review

Origins, evolution, and phenotypic impact of new genes

  • First Published July 22, 2010
Resource

The ANISEED database: Digital representation, formalization, and elucidation of a chordate developmental program

  • First Published July 20, 2010
Research

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

  • First Published July 20, 2010
Resource

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

  • First Published July 19, 2010
Research

Gene amplification as double minutes or homogeneously staining regions in solid tumors: Origin and structure

  • First Published July 14, 2010
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