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Method

SvABA: genome-wide detection of structural variants and indels by local assembly

  • First Published March 13, 2018
Research

Arabidopsis thaliana transposons and gene regulatory regions" > Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

  • First Published March 12, 2018
Research

Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation" > Epigenetic activation of meiotic recombination near Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation

  • First Published March 12, 2018
Research

Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals

  • First Published March 2, 2018
Research

Intrinsic DNA binding properties demonstrated for lineage-specifying basic helix-loop-helix transcription factors

  • First Published March 2, 2018
Method

Genome-reconstruction for eukaryotes from complex natural microbial communities

  • First Published March 1, 2018
Research

Selective maternal seeding and environment shape the human gut microbiome

  • First Published March 1, 2018
Method

CRISPR RNAs trigger innate immune responses in human cells

  • First Published February 22, 2018
Research

Conserved microRNA targeting reveals preexisting gene dosage sensitivities that shaped amniote sex chromosome evolution

  • First Published February 15, 2018
Research

Enhancer RNA profiling predicts transcription factor activity

  • First Published February 15, 2018
Research

Widespread and precise reprogramming of yeast protein–genome interactions in response to heat shock

  • First Published February 14, 2018
Method

FIND: difFerential chromatin INteractions Detection using a spatial Poisson process

  • First Published February 12, 2018
Research

3′ UTR lengthening as a novel mechanism in regulating cellular senescence

  • First Published February 12, 2018
Method

SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification

  • First Published February 9, 2018
Research

ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters

  • First Published February 2, 2018
Research

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures

  • First Published February 2, 2018
Research

Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control

  • First Published January 24, 2018
Method

KRAS with CRISPR-Cas9 controls tumor growth" > Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth

  • First Published January 11, 2018
Method

Reconstructing differentiation networks and their regulation from time series single-cell expression data

  • First Published January 9, 2018
Research

cis-regulatory activity" > Local sequence features that influence AP-1 cis-regulatory activity

  • First Published January 5, 2018
Corrigendum

Corrigendum: Discovery and genotyping of structural variation from long-read haploid genome sequence data

  • First Published January 2, 2018
Method

Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

  • First Published December 22, 2017
Research

Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis

  • First Published December 22, 2017
Research

The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes

  • First Published December 22, 2017
Method

Caenorhabditis elegans reference genome" > MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome

  • First Published December 22, 2017
Research

Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

  • First Published December 19, 2017
Research

Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast

  • First Published December 18, 2017
Research

Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs

  • First Published December 18, 2017
Research

Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data

  • First Published December 18, 2017
Research

Saturation mutagenesis reveals manifold determinants of exon definition

  • First Published December 14, 2017
Research

Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection

  • First Published December 13, 2017
Resource

The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting

  • First Published December 12, 2017
Research

Drosophila genus" > Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus

  • First Published December 12, 2017
Research

DNA mismatch repair preferentially protects genes from mutation

  • First Published December 12, 2017
Method

Integrated analysis of motif activity and gene expression changes of transcription factors

  • First Published December 12, 2017
Research

H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2

  • First Published December 11, 2017
Method

Detecting differential copy number variation between groups of samples

  • First Published December 11, 2017
Method

Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

  • First Published December 8, 2017
Method

SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells

  • First Published December 5, 2017
Resource

Impact of regulatory variation across human iPSCs and differentiated cells

  • First Published December 5, 2017
Method

SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site

  • First Published December 1, 2017
Method

Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome

  • First Published December 1, 2017
Corrigendum

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

  • First Published December 1, 2017
Reviewer Index

Reviewer Index, Volume 27, 2017

  • First Published December 1, 2017
Method

ABCA4 midigenes reveal the full splice spectrum of all reported noncanonical splice site variants in Stargardt disease" > ABCA4 midigenes reveal the full splice spectrum of all reported noncanonical splice site variants in Stargardt disease

  • First Published November 21, 2017
Research

Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

  • First Published November 21, 2017
Method

Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing

  • First Published November 16, 2017
Method

An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics

  • First Published November 15, 2017
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