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Research

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers

  • First Published December 18, 2018
Research

Nucleosome remodeling at origins of global genome–nucleotide excision repair occurs at the boundaries of higher-order chromatin structure

  • First Published December 14, 2018
Research

Hormone-control regions mediate steroid receptor–dependent genome organization

  • First Published December 14, 2018
Research

A quantitative framework for characterizing the evolutionary history of mammalian gene expression

  • First Published December 14, 2018
Research

Transposable element insertions in fission yeast drive adaptation to environmental stress

  • First Published December 12, 2018
Research

Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock

  • First Published December 6, 2018
Method

Minerva: an alignment- and reference-free approach to deconvolve Linked-Reads for metagenomics

  • First Published December 6, 2018
Resource

Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees

  • First Published December 4, 2018
Reviewer Index

Reviewer Index, Volume 28, 2018

  • First Published December 3, 2018
Research

Arabidopsis metabolome reveals mediators of the epigenotype-phenotype map" > Epigenetic mapping of the Arabidopsis metabolome reveals mediators of the epigenotype-phenotype map

  • First Published November 30, 2018
Research

Accelerated rates of large-scale mutations in the presence of copper and nickel

  • First Published November 28, 2018
Research

Drosophila regeneration" > Damage-responsive elements in Drosophila regeneration

  • First Published November 20, 2018
Method

Quantification of somatic mutation flow across individual cell division events by lineage sequencing

  • First Published November 20, 2018
Research

Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions

  • First Published November 19, 2018
Research

ERAP2 transcripts under balancing selection" > Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

  • First Published November 16, 2018
Method

DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA

  • First Published November 9, 2018
Method

Defining TP53 pioneering capabilities with competitive nucleosome binding assays

  • First Published November 8, 2018
Resource

Cannabis sativa identifies extensive rearrangements at the THC/CBD acid synthase loci" > A physical and genetic map of Cannabis sativa identifies extensive rearrangements at the THC/CBD acid synthase loci

  • First Published November 8, 2018
Method

HD-Marker: a highly multiplexed and flexible approach for targeted genotyping of more than 10,000 genes in a single-tube assay

  • First Published November 8, 2018
Method

SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA

  • First Published November 7, 2018
Research

Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate

  • First Published November 6, 2018
Research

Noncoding transcription influences the replication initiation program through chromatin regulation

  • First Published November 6, 2018
Corrigendum

Drosophila" > Corrigendum: Tempo and mode of regulatory evolution in Drosophila

  • First Published November 1, 2018
Research

Evolutionary conservation of Y Chromosome ampliconic gene families despite extensive structural variation

  • First Published October 31, 2018
Research

LTRs activated by Epstein-Barr virus–induced transformation of B cells alter the transcriptome

  • First Published October 31, 2018
Research

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes

  • First Published October 24, 2018
Research

Expanding heterochromatin reveals discrete subtelomeric domains delimited by chromatin landscape transitions

  • First Published October 24, 2018
Method

NanoPARE: parallel analysis of RNA 5′ ends from low-input RNA

  • First Published October 24, 2018
Research

Ranking noncanonical 5′ splice site usage by genome-wide RNA-seq analysis and splicing reporter assays

  • First Published October 24, 2018
Research

Global transcriptional activity dynamics reveal functional enhancer RNAs

  • First Published October 23, 2018
Research

Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians

  • First Published October 23, 2018
Method

Targeted genotyping of variable number tandem repeats with adVNTR

  • First Published October 23, 2018
Research

PRDM9 expression impacts the pan-cancer genomic landscape" > Aberrant PRDM9 expression impacts the pan-cancer genomic landscape

  • First Published October 19, 2018
Method

Chromosome assembly of large and complex genomes using multiple references

  • First Published October 19, 2018
Resource

Maftools: efficient and comprehensive analysis of somatic variants in cancer

  • First Published October 19, 2018
Research

Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

  • First Published October 17, 2018
Method

High-salt–recovered sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies

  • First Published October 4, 2018
Research

Drosophila" > Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila

  • First Published October 2, 2018
Research

The gene repressor complex NuRD interacts with the histone variant H3.3 at promoters of active genes

  • First Published September 25, 2018
Method

High-throughput characterization of genetic effects on DNA–protein binding and gene transcription

  • First Published September 25, 2018
Resource

The genomic architecture and molecular evolution of ant odorant receptors

  • First Published September 24, 2018
Research

Metagenomic analysis with strain-level resolution reveals fine-scale variation in the human pregnancy microbiome

  • First Published September 19, 2018
Method

Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS)

  • First Published September 19, 2018
Research

Young genes have distinct gene structure, epigenetic profiles, and transcriptional regulation

  • First Published September 19, 2018
Research

Pristionchus nematodes" > Deep taxon sampling reveals the evolutionary dynamics of novel gene families in Pristionchus nematodes

  • First Published September 19, 2018
Research

Crosstalk between alternative polyadenylation and miRNAs in the regulation of protein translational efficiency

  • First Published September 18, 2018
Method

Transcriptional fates of human-specific segmental duplications in brain

  • First Published September 18, 2018
Research

Gene regulation underlies environmental adaptation in house mice

  • First Published September 7, 2018
Corrigendum

Corrigendum: Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

  • First Published September 4, 2018
Research

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

  • First Published August 31, 2018
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