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Research

Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells

  • First Published October 18, 2023
Research

Transposon accumulation at xenobiotic gene family loci in aphids

  • First Published October 18, 2023
Method

ESICCC as a systematic computational framework for evaluation, selection, and integration of cell-cell communication inference methods

  • First Published October 12, 2023
Research

Deciphering D4Z4 CpG methylation gradients in fascioscapulohumeral muscular dystrophy using nanopore sequencing

  • First Published October 5, 2023
Research

Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development

  • First Published October 5, 2023
Research

Comprehensive isoform-level analysis reveals the contribution of alternative isoforms to venom evolution and repertoire diversity

  • First Published October 5, 2023
Research

The rate of de novo structural variation is increased in in vitro–produced offspring and preferentially affects the paternal genome

  • First Published October 4, 2023
Resource

An organism-wide ATAC-seq peak catalog for the bovine and its use to identify regulatory variants

  • First Published September 26, 2023
Research

Analyses of 600+ insect genomes reveal repetitive element dynamics and highlight biodiversity-scale repeat annotation challenges

  • First Published September 22, 2023
Resource

Genetic features and genomic targets of human KRAB-zinc finger proteins

  • First Published September 20, 2023
Resource

Single-nucleus transcriptomic mapping uncovers targets for traumatic brain injury

  • First Published September 20, 2023
Resource

Acomys) ear" > Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse (Acomys) ear

  • First Published September 19, 2023
Research

Transposable elements drive the evolution of metazoan zinc finger genes

  • First Published September 15, 2023
Method

N6-methyladenosine modifications reveal functional genetic variants in human tissues" > Allele-specific RNA N6-methyladenosine modifications reveal functional genetic variants in human tissues

  • First Published September 15, 2023
Research

Bos species" > A Chinese indicine pangenome reveals a wealth of novel structural variants introgressed from other Bos species

  • First Published September 15, 2023
Research

Nucleosome repositioning in chronic lymphocytic leukemia

  • First Published September 12, 2023
Research

Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features

  • First Published September 12, 2023
Research

Copy number variation alters local and global mutational tolerance

  • First Published August 31, 2023
Research

Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits

  • First Published August 25, 2023
Method

Accurate and fast graph-based pangenome annotation and clustering with ggCaller

  • First Published August 24, 2023
Method

Fast and accurate out-of-core PCA framework for large scale biobank data

  • First Published August 24, 2023
Research

Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotype organization

  • First Published August 17, 2023
Research

The predicted RNA-binding protein regulome of axonal mRNAs

  • First Published August 15, 2023
Research

Chlamydomonas reinhardtii" > Telomerase-independent survival leads to a mosaic of complex subtelomere rearrangements in Chlamydomonas reinhardtii

  • First Published August 14, 2023
Method

Dissecting and improving gene regulatory network inference using single-cell transcriptome data

  • First Published August 14, 2023
Method

Ultrafast genome-wide inference of pairwise coalescence times

  • First Published August 10, 2023
Method

k using minimum decycling sets" > Efficient minimizer orders for large values of k using minimum decycling sets

  • First Published August 9, 2023
Method

Partial alignment of multislice spatially resolved transcriptomics data

  • First Published August 8, 2023
Method

Assessing transcriptomic reidentification risks using discriminative sequence models

  • First Published August 4, 2023
Research

Genetic inhibitors of APOBEC3B-induced mutagenesis

  • First Published August 2, 2023
Research

ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development

  • First Published August 2, 2023
Method

A transcriptome-based single-cell biological age model and resource for tissue-specific aging measures

  • First Published July 31, 2023
Method

Diffusion-enhanced characterization of 3D chromatin structure reveals its linkage to gene regulatory networks and the interactome

  • First Published July 25, 2023
Research

Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins

  • First Published July 24, 2023
Method

Inferring and comparing metabolism across heterogeneous sets of annotated genomes using AuCoMe

  • First Published July 19, 2023
Research

Historical RNA expression profiles from the extinct Tasmanian tiger

  • First Published July 18, 2023
Research

Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells

  • First Published July 18, 2023
Method

Unraveling the palindromic and nonpalindromic motifs of retroviral integration site sequences by statistical mixture models

  • First Published July 18, 2023
Research

Ultra-long-range interactions between active regulatory elements

  • First Published July 14, 2023
Research

Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution

  • First Published July 13, 2023
Research

Poecilia reticulata" > Extensive variation in germline de novo mutations in Poecilia reticulata

  • First Published July 13, 2023
Research

Drosophila melanogaster" > Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster

  • First Published July 13, 2023
Method

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

  • First Published July 11, 2023
Method

Large-scale detection and characterization of interchromosomal rearrangements in normozoospermic bulls using massive genotype and phenotype data sets

  • First Published July 6, 2023
Method

Genomic sketching with multiplicities and locality-sensitive hashing using Dashing 2

  • First Published July 6, 2023
Method

Leveraging protein language models for accurate multiple sequence alignments

  • First Published July 6, 2023
Method

Efficient mapping of accurate long reads in minimizer space with mapquik

  • First Published June 30, 2023
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