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Research

Ultra-long-range interactions between active regulatory elements

  • First Published July 14, 2023
Research

Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution

  • First Published July 13, 2023
Research

Poecilia reticulata" > Extensive variation in germline de novo mutations in Poecilia reticulata

  • First Published July 13, 2023
Research

Drosophila melanogaster" > Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster

  • First Published July 13, 2023
Method

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

  • First Published July 11, 2023
Method

Large-scale detection and characterization of interchromosomal rearrangements in normozoospermic bulls using massive genotype and phenotype data sets

  • First Published July 6, 2023
Method

Genomic sketching with multiplicities and locality-sensitive hashing using Dashing 2

  • First Published July 6, 2023
Method

Leveraging protein language models for accurate multiple sequence alignments

  • First Published July 6, 2023
Method

Efficient mapping of accurate long reads in minimizer space with mapquik

  • First Published June 30, 2023
Method

Fast inference of genetic recombination rates in biobank scale data

  • First Published June 22, 2023
Method

Modeling and predicting cancer clonal evolution with reinforcement learning

  • First Published June 21, 2023
Method

Deriving confidence intervals for mutation rates across a wide range of evolutionary distances using FracMinHash

  • First Published June 21, 2023
Corrigendum

Neurospora crassa" > Corrigendum: Chromatin structure influences rate and spectrum of spontaneous mutations in Neurospora crassa

  • First Published June 16, 2023
Method

Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models

  • First Published June 14, 2023
Method

Minimal positional substring cover is a haplotype threading alternative to Li and Stephens model

  • First Published June 14, 2023
Resource

The fine-scale recombination rate variation and associations with genomic features in a butterfly

  • First Published June 12, 2023
Method

Accurate integration of multiple heterogeneous single-cell RNA-seq data sets by learning contrastive biological variation

  • First Published June 12, 2023
Method

Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets

  • First Published June 12, 2023
Method

Debiased personalized gene coexpression networks for population-scale scRNA-seq data

  • First Published June 9, 2023
Research

Integration site–dependent HIV-1 promoter activity shapes host chromatin conformation

  • First Published June 9, 2023
Method

Targeted, programmable, and precise tandem duplication in the mammalian genome

  • First Published June 9, 2023
Resource

Brassica napus using a pooled CRISPR library" > Genome-scale targeted mutagenesis in Brassica napus using a pooled CRISPR library

  • First Published June 8, 2023
Research

Plant polymerase IV sensitizes chromatin through histone modifications to preclude spread of silencing into protein-coding domains

  • First Published June 5, 2023
Method

Efficient taxa identification using a pangenome index

  • First Published May 31, 2023
Method

Genealogical inference and more flexible sequence clustering using iterative-PopPUNK

  • First Published May 30, 2023
Method

Extremely fast construction and querying of compacted and colored de Bruijn graphs with GGCAT

  • First Published May 30, 2023
Resource

Discordant calls across genotype discovery approaches elucidate variants with systematic errors

  • First Published May 30, 2023
Method

A fast and scalable method for inferring phylogenetic networks from trees by aligning lineage taxon strings

  • First Published May 22, 2023
Research

Variation in histone configurations correlates with gene expression across nine inbred strains of mice

  • First Published May 22, 2023
Method

Entropy predicts sensitivity of pseudorandom seeds

  • First Published May 22, 2023
Method

Unsupervised contrastive peak caller for ATAC-seq

  • First Published May 22, 2023
Method

Enabling tradeoffs in privacy and utility in genomic data Beacons and summary statistics

  • First Published May 22, 2023
Method

Leveraging family data to design Mendelian randomization that is provably robust to population stratification

  • First Published May 17, 2023
Method

Efficient and accurate KIR and HLA genotyping with massively parallel sequencing data

  • First Published May 11, 2023
Research

Gaps and complex structurally variant loci in phased genome assemblies

  • First Published May 10, 2023
Resource

Comparing genomic and epigenomic features across species using the WashU Comparative Epigenome Browser

  • First Published May 8, 2023
Research

Dynamic modulation of genomic enhancer elements in the suprachiasmatic nucleus, the site of the mammalian circadian clock

  • First Published May 8, 2023
Method

Multiplexed long-read plasmid validation and analysis using OnRamp

  • First Published May 8, 2023
Research

Genomic insights into metabolic flux in hummingbirds

  • First Published May 8, 2023
Research

Xiphophorus species provide new insights into microevolution, hybrid incompatibility, and epistasis" > High resolution genomes of multiple Xiphophorus species provide new insights into microevolution, hybrid incompatibility, and epistasis

  • First Published May 5, 2023
Perspective

Challenges and considerations for reproducibility of STARR-seq assays

  • First Published May 2, 2023
Method

CRISPR-Cas9-based repeat depletion for high-throughput genotyping of complex plant genomes

  • First Published May 1, 2023
Research

Msh3 in the propensity for genome-wide short tandem repeat expansions in mice" > A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeat expansions in mice

  • First Published May 1, 2023
Research

Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity

  • First Published May 1, 2023
Method

Accurate transcriptome-wide identification and quantification of alternative polyadenylation from RNA-seq data with APAIQ

  • First Published April 28, 2023
Research

Incomplete erasure of histone marks during epigenetic reprogramming in medaka early development

  • First Published April 28, 2023
Research

MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain

  • First Published April 26, 2023
Resource

A single-cell transcriptome atlas of the maturing zebrafish telencephalon

  • First Published April 18, 2023
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