Your search for returned 6,373 results
Perspective
Translational genomics: The challenge of developing cancer biomarkers
- First Published February 1, 2012
Research
Microevolution of extensively drug-resistant tuberculosis in Russia
- First Published January 31, 2012
Research
Retrotransposon profiling of RNA polymerase III initiation sites
- First Published January 27, 2012
Research
Evolutionary rate covariation reveals shared functionality and coexpression of genes
- First Published January 27, 2012
Research
A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver
- First Published January 27, 2012
Resource
Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs
- First Published January 26, 2012
Method
Unified modeling of gene duplication, loss, and coalescence using a locus tree
- First Published January 23, 2012
Method
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture
- First Published January 20, 2012
Research
The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients
- First Published January 20, 2012
Research
Drosophila embryo" > The TAGteam motif facilitates binding of 21 sequence-specific transcription factors in the Drosophila embryo
- First Published January 13, 2012
Research
An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement
- First Published January 10, 2012
Research
HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter" > HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter
- First Published January 10, 2012
Research
Saccharomyces cerevisiae Ty1 retrotransposon" > A nucleosomal surface defines an integration hotspot for the Saccharomyces cerevisiae Ty1 retrotransposon
- First Published January 4, 2012
Research
Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots
- First Published January 4, 2012
Method
Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling
- First Published January 4, 2012
Research
Comparative RNA sequencing reveals substantial genetic variation in endangered primates
- First Published December 29, 2011
Method
Ultraconserved elements are novel phylogenomic markers that resolve placental mammal phylogeny when combined with species-tree analysis
- First Published December 29, 2011
Research
The human phosphotyrosine signaling network: Evolution and hotspots of hijacking in cancer
- First Published December 22, 2011
Research
Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent
- First Published December 19, 2011
Research
Whole genome sequencing of matched primary and metastatic acral melanomas
- First Published December 19, 2011
Method
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases
- First Published December 19, 2011
Research
Cooperation between Polycomb and androgen receptor during oncogenic transformation
- First Published December 16, 2011
Resource
Efficient de novo assembly of large genomes using compressed data structures
- First Published December 7, 2011
Research
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
- First Published December 7, 2011
Research
SLCO1B1 variation and methotrexate disposition" > Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition
- First Published December 6, 2011
Resource
GAGE: A critical evaluation of genome assemblies and assembly algorithms
- First Published December 6, 2011
Research
Disclosing pathogenic genetic variants to research participants: Quantifying an emerging ethical responsibility
- First Published December 6, 2011
Research
Drosophila melanogaster" > Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster
- First Published December 1, 2011
Research
Evolutionary history of novel genes on the tammar wallaby Y chromosome: Implications for sex chromosome evolution
- First Published November 29, 2011
Method
Genome-wide detection of natural selection in African Americans pre- and post-admixture
- First Published November 29, 2011
Method
Estimation of alternative splicing variability in human populations
- First Published November 23, 2011
Resource
Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis
- First Published November 22, 2011
Resource
High-resolution mapping of open chromatin in the rice genome
- First Published November 22, 2011
Research
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
- First Published November 21, 2011
Research
Arabidopsis genome-wide variations before and after meiosis and meiotic recombination by resequencing Landsberg erecta and all four products of a single meiosis" > Analysis of Arabidopsis genome-wide variations before and after meiosis and meiotic recombination by resequencing Landsberg erecta and all four products of a single meiosis
- First Published November 21, 2011
Research
DMD gene" > Aberrant firing of replication origins potentially explains intragenic nonrecurrent rearrangements within genes, including the human DMD gene
- First Published November 16, 2011
Research
Interlocus gene conversion events introduce deleterious mutations into at least 1% of human genes associated with inherited disease
- First Published November 16, 2011
Research
Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells
- First Published November 16, 2011
Research
Developmental control of gene copy number by repression of replication initiation and fork progression
- First Published November 16, 2011
Method
Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA
- First Published November 16, 2011
Method
Calling amplified haplotypes in next generation tumor sequence data
- First Published November 16, 2011
Research
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription
- First Published November 15, 2011
Research
Lactococcus lactis can be reproduced by experimental evolution" > Microbial domestication signatures of Lactococcus lactis can be reproduced by experimental evolution
- First Published November 11, 2011
Resource
Simultaneous structural variation discovery among multiple paired-end sequenced genomes
- First Published November 2, 2011
Research
Deep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human embryonic stem cells
- First Published October 31, 2011
Research
Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development
- First Published October 31, 2011
Research
Leishmania" > Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
- First Published October 28, 2011
Research
Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance" > Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
- First Published October 28, 2011
Research
Fusobacterium with colorectal carcinoma" > Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
- First Published October 18, 2011
Research
Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma" > Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
- First Published October 18, 2011
Research
Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters
- First Published October 18, 2011
Research
Drosophila and other metazoa" > Evidence of abundant stop codon readthrough in Drosophila and other metazoa
- First Published October 12, 2011
Method
Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes
- First Published October 12, 2011
Method
New families of human regulatory RNA structures identified by comparative analysis of vertebrate genomes
- First Published October 12, 2011
Research
A matter of life or death: How microsatellites emerge in and vanish from the human genome
- First Published October 12, 2011
Research
Unique DNA methylome profiles in CpG island methylator phenotype colon cancers
- First Published October 11, 2011
Research
Genomic analysis of circulating cell-free DNA infers breast cancer dormancy
- First Published October 11, 2011
Research
Changes in exon–intron structure during vertebrate evolution affect the splicing pattern of exons
- First Published October 5, 2011
Research
Populus" > Contrasting patterns of evolution following whole genome versus tandem duplication events in Populus
- First Published October 5, 2011
Method
Accurate identification of A-to-I RNA editing in human by transcriptome sequencing
- First Published September 29, 2011
Research
Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome
- First Published September 28, 2011
Research
Extensive variation and low heritability of DNA methylation identified in a twin study
- First Published September 26, 2011
Research
Genomic basis of endosymbiont-conferred protection against an insect parasitoid
- First Published September 23, 2011
Research
Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant
- First Published September 23, 2011
Resource
Arabidopsis" > High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis
- First Published September 22, 2011
Method
Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets
- First Published September 22, 2011
Research
A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast
- First Published September 19, 2011
Resource
Assemblathon 1: A competitive assessment of de novo short read assembly methods
- First Published September 16, 2011
Method
Mutual exclusivity analysis identifies oncogenic network modules
- First Published September 9, 2011
Research
Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states
- First Published September 9, 2011
Research
Widespread signatures of recent selection linked to nucleosome positioning in the human lineage
- First Published September 8, 2011
Method
A metabolomic and systems biology perspective on the brain of the Fragile X syndrome mouse model
- First Published September 7, 2011
Method
Characterization of complex chromosomal rearrangements by targeted capture and next-generation sequencing
- First Published September 2, 2011
Research
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells
- First Published September 2, 2011
Research
Homozygosity mapping and targeted genomic sequencing reveal the gene responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred
- First Published September 1, 2011
Research
The human gut virome: Inter-individual variation and dynamic response to diet
- First Published August 31, 2011
Method
Efficient cross-species capture hybridization and next-generation sequencing of mitochondrial genomes from noninvasively sampled museum specimens
- First Published August 31, 2011
Method
Discriminative prediction of mammalian enhancers from DNA sequence
- First Published August 29, 2011
Research
Epigenetic regulation of normal human mammary cell type–specific miRNAs
- First Published August 26, 2011
Method
A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data
- First Published August 26, 2011
Research
Emergence of male-biased genes on the chicken Z-chromosome: Sex-chromosome contrasts between male and female heterogametic systems
- First Published August 25, 2011
Research
Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network
- First Published August 24, 2011
Research
Relating CNVs to transcriptome data at fine resolution: Assessment of the effect of variant size, type, and overlap with functional regions
- First Published August 23, 2011