Your search for returned 6,372 results
Research
Canonical nucleosome organization at promoters forms during genome activation
- First Published November 27, 2013
Method
cis-regulatory landscapes in vertebrates" > A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates
- First Published November 25, 2013
Research
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia
- First Published November 21, 2013
Method
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases
- First Published November 19, 2013
Method
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- First Published November 19, 2013
Research
The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages
- First Published November 18, 2013
Research
Genomic and transcriptomic plasticity in treatment-naïve ovarian cancer
- First Published November 12, 2013
Method
Discovery of recurrent structural variants in nasopharyngeal carcinoma
- First Published November 8, 2013
Research
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
- First Published November 7, 2013
Research
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
- First Published November 6, 2013
Method
Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
- First Published October 31, 2013
Method
Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing
- First Published October 31, 2013
Resource
Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps
- First Published October 29, 2013
Research
The altered landscape of the human skin microbiome in patients with primary immunodeficiencies
- First Published October 29, 2013
Resource
Variation Ontology for annotation of variation effects and mechanisms
- First Published October 25, 2013
Resource
Improved exome prioritization of disease genes through cross-species phenotype comparison
- First Published October 25, 2013
Research
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
- First Published October 24, 2013
Research
Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs
- First Published October 22, 2013
Resource
Genome-wide high resolution parental-specific DNA and histone methylation maps uncover patterns of imprinting regulation in maize
- First Published October 16, 2013
Research
Gene duplication and neofunctionalization: POLR3G and POLR3GL
- First Published October 9, 2013
Research
Maize centromeres expand and adopt a uniform size in the genetic background of oat
- First Published October 7, 2013
Research
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
- First Published October 3, 2013
Research
A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen
- First Published October 2, 2013
Research
Hominoid fission of chromosome 14/15 and the role of segmental duplications
- First Published September 27, 2013
Research
High-throughput chromatin motion tracking in living yeast reveals the flexibility of the fiber throughout the genome
- First Published September 27, 2013
Research
The evolution of evolvability in microRNA target sites in vertebrates
- First Published September 27, 2013
Research
3′ UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts
- First Published September 26, 2013
Research
Large-scale hypomethylated blocks associated with Epstein-Barr virus–induced B-cell immortalization
- First Published September 25, 2013
Research
Monodelphis domestica" > Chromosome-wide profiling of X-chromosome inactivation and epigenetic states in fetal brain and placenta of the opossum, Monodelphis domestica
- First Published September 24, 2013
Method
Single-cell mutational profiling and clonal phylogeny in cancer
- First Published September 20, 2013
Research
Heliconius butterflies" > Genome-wide evidence for speciation with gene flow in Heliconius butterflies
- First Published September 17, 2013
Research
Derived variants at six genes explain nearly half of size reduction in dog breeds
- First Published September 11, 2013
Research
Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division
- First Published September 11, 2013
Research
Identifying multiple causative genes at a single GWAS locus
- First Published September 4, 2013
Research
Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments
- First Published September 3, 2013
Resource
Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis
- First Published September 3, 2013
Research
HOXD13 mutations" > Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations
- First Published August 30, 2013
Research
H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction
- First Published August 29, 2013
Research
The influence of genomic context on mutation patterns in the human genome inferred from rare variants
- First Published August 29, 2013
Research
The shared genomic architecture of human nucleolar organizer regions
- First Published August 29, 2013
Research
Multiple RNA recognition patterns during microRNA biogenesis in plants
- First Published August 29, 2013
Method
Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation
- First Published August 15, 2013
Method
Defining cell-type specificity at the transcriptional level in human disease
- First Published August 15, 2013
Resource
Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach
- First Published August 15, 2013
Research
Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer
- First Published August 12, 2013
Method
Analysis and correction of crosstalk effects in pathway analysis
- First Published August 9, 2013
Method
Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants
- First Published August 6, 2013
Method
Drosophila genomes" > Efficient identification of Y chromosome sequences in the human and Drosophila genomes
- First Published August 6, 2013
Resource
Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators
- First Published August 6, 2013
Research
RNA–DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA
- First Published August 2, 2013
Research
Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase
- First Published August 1, 2013
Research
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
- First Published July 26, 2013
Method
Directed shotgun proteomics guided by saturated RNA-seq identifies a complete expressed prokaryotic proteome
- First Published July 22, 2013
Resource
Coelacanth genomes reveal signatures for evolutionary transition from water to land
- First Published July 22, 2013
Research
GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination
- First Published July 18, 2013
Method
FST: The impact of rare variants" > Estimating and interpreting FST: The impact of rare variants
- First Published July 16, 2013
Research
Bubble-seq analysis of the human genome reveals distinct chromatin-mediated mechanisms for regulating early- and late-firing origins
- First Published July 16, 2013
Research
Lamin A/C-promoter interactions specify chromatin state–dependent transcription outcomes
- First Published July 16, 2013
Research
Evolution and diversity of copy number variation in the great ape lineage
- First Published July 3, 2013
Method
Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data
- First Published July 1, 2013
Perspective
Understanding the regulatory and transcriptional complexity of the genome through structure
- First Published July 1, 2013
Perspective
Insights into neural crest development and evolution from genomic analysis
- First Published July 1, 2013
Perspective
Comparative genomics as a tool to understand evolution and disease
- First Published July 1, 2013
Research
De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements
- First Published June 28, 2013
Research
Caenorhabditis elegans" > Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans
- First Published June 28, 2013
Method
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
- First Published June 26, 2013
Method
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
- First Published June 26, 2013
Research
Sympatric chimpanzees and gorillas harbor convergent gut microbial communities
- First Published June 26, 2013
Resource
Caenorhabditis elegans" > The million mutation project: A new approach to genetics in Caenorhabditis elegans
- First Published June 25, 2013
Research
The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease
- First Published June 25, 2013
Research
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
- First Published June 20, 2013
Research
Comparative analysis of mammalian Y chromosomes illuminates ancestral structure and lineage-specific evolution
- First Published June 20, 2013
Research
DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast
- First Published June 20, 2013
Research
The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome
- First Published June 19, 2013
Research
Frac-seq reveals isoform-specific recruitment to polyribosomes
- First Published June 19, 2013
Research
Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay
- First Published June 13, 2013
Method
Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations
- First Published June 6, 2013
Research
Epigenome-wide inheritance of cytosine methylation variants in a recombinant inbred population
- First Published June 5, 2013
Research
The maize methylome influences mRNA splice sites and reveals widespread paramutation-like switches guided by small RNA
- First Published June 5, 2013
Research
Comprehensive genome- and transcriptome-wide analyses of mutations associated with microsatellite instability in Korean gastric cancers
- First Published June 4, 2013