Your search for returned 6,372 results
Research
Drosophila-like dosage compensation mechanism in a reptile lineage" > Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage
- First Published November 13, 2017
Research
Comparative genome analysis of programmed DNA elimination in nematodes
- First Published November 8, 2017
Method
Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair
- First Published November 7, 2017
Research
Deep learning of the regulatory grammar of yeast 5′ untranslated regions from 500,000 random sequences
- First Published November 2, 2017
Method
GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly
- First Published November 2, 2017
Resource
C. elegans" > Quantitative RNA-seq meta-analysis of alternative exon usage in C. elegans
- First Published October 31, 2017
Research
Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation
- First Published October 27, 2017
Research
Assessing the reliability of spike-in normalization for analyses of single-cell RNA sequencing data
- First Published October 13, 2017
Research
Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons
- First Published October 13, 2017
Method
Single-cell sequencing data reveal widespread recurrence and loss of mutational hits in the life histories of tumors
- First Published October 13, 2017
Research
Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes
- First Published October 12, 2017
Method
Accounting for GC-content bias reduces systematic errors and batch effects in ChIP-seq data
- First Published October 12, 2017
Research
Nascent RNA sequencing reveals a dynamic global transcriptional response at genes and enhancers to the natural medicinal compound celastrol
- First Published October 12, 2017
Resource
A genome-wide interactome of DNA-associated proteins in the human liver
- First Published October 11, 2017
Method
cis-acting genetic variation using allelic fold change" > Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change
- First Published October 11, 2017
Method
Co-expression networks reveal the tissue-specific regulation of transcription and splicing
- First Published October 11, 2017
Research
Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways
- First Published October 6, 2017
Corrigendum
Corrigendum: A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy
- First Published October 3, 2017
Research
Massive reshaping of genome–nuclear lamina interactions during oncogene-induced senescence
- First Published September 15, 2017
Research
S. cerevisiae and S. pombe" > Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe
- First Published September 15, 2017
Research
Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity
- First Published September 14, 2017
Research
Redundant and incoherent regulations of multiple phenotypes suggest microRNAs’ role in stability control
- First Published September 13, 2017
Method
Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints
- First Published September 13, 2017
Research
Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation
- First Published September 13, 2017
Research
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity
- First Published September 13, 2017
Method
Detection of long repeat expansions from PCR-free whole-genome sequence data
- First Published September 8, 2017
Method
Solid-phase reverse transfection for intracellular delivery of functionally active proteins
- First Published September 5, 2017
Research
RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system
- First Published September 1, 2017
Method
Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation
- First Published September 1, 2017
Corrigendum
Corrigendum: Transcriptome analyses of rhesus monkey preimplantation embryos reveal a reduced capacity for DNA double-strand break repair in primate oocytes and early embryos
- First Published September 1, 2017
Corrigendum
Corrigendum: Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland
- First Published September 1, 2017
Corrigendum
Corrigendum: The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2
- First Published September 1, 2017
Resource
An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms
- First Published August 30, 2017
Research
Transposable elements are the primary source of novelty in primate gene regulation
- First Published August 30, 2017
Method
The Mobile Element Locator Tool (MELT): population-scale mobile element discovery and biology
- First Published August 30, 2017
Method
HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient
- First Published August 30, 2017
Method
Detection of structural mosaicism from targeted and whole-genome sequencing data
- First Published August 30, 2017
Method
Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies
- First Published August 28, 2017
Research
Arabidopsis transposons identifies a unique and conserved genome expression strategy for Ty1/Copia retroelements" > A genome-wide transcriptome and translatome analysis of Arabidopsis transposons identifies a unique and conserved genome expression strategy for Ty1/Copia retroelements
- First Published August 7, 2017
Research
HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets
- First Published August 7, 2017
Resource
Assembly and analysis of 100 full MHC haplotypes from the Danish population
- First Published August 3, 2017
Corrigendum
Corrigendum: TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code
- First Published August 1, 2017
Research
Anopheles malaria mosquitoes" > Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes
- First Published July 26, 2017
Research
The evolution of duplicate gene expression in mammalian organs
- First Published July 25, 2017
Research
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
- First Published July 24, 2017
Research
Recruitment of histone modifications to assist mRNA dosage maintenance after degeneration of cytosine DNA methylation during animal evolution
- First Published July 18, 2017
Method
Detecting ancient positive selection in humans using extended lineage sorting
- First Published July 18, 2017
Method
HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology
- First Published July 18, 2017
Research
Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of ST131" > Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of ST131
- First Published July 18, 2017
Resource
Annotation and cluster analysis of spatiotemporal- and sex-related lncRNA expression in rhesus macaque brain
- First Published July 7, 2017
Method
Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs
- First Published July 6, 2017
Research
Trans-splicing enhances translational efficiency in C. elegans" > Trans-splicing enhances translational efficiency in C. elegans
- First Published July 6, 2017
Research
Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia
- First Published July 5, 2017
Research
The house fly Y Chromosome is young and minimally differentiated from its ancient X Chromosome partner
- First Published June 15, 2017
Research
Cryptococcus neoformans" > Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans
- First Published June 13, 2017
Research
DDX54 regulates transcriptome dynamics during DNA damage response
- First Published June 8, 2017
Research
Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion" > Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion
- First Published June 6, 2017
Research
Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer
- First Published May 25, 2017
Research
YY1 and CTCF orchestrate a 3D chromatin looping switch during early neural lineage commitment
- First Published May 23, 2017
Research
Arabidopsis" > Dehydration stress extends mRNA 3′ untranslated regions with noncoding RNA functions in Arabidopsis
- First Published May 18, 2017
Resource
GenomeVIP: a cloud platform for genomic variant discovery and interpretation
- First Published May 18, 2017
Research
Long terminal repeats power evolution of genes and gene expression programs in mammalian oocytes and zygotes
- First Published May 18, 2017
Research
DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation
- First Published May 16, 2017
Research
Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes
- First Published May 16, 2017
Research
Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand
- First Published May 16, 2017
Research
Single-cell sequencing deciphers a convergent evolution of copy number alterations from primary to circulating tumor cells
- First Published May 9, 2017
Research
The identification and functional annotation of RNA structures conserved in vertebrates
- First Published May 9, 2017
Research
Heritable L1 retrotransposition in the mouse primordial germline and early embryo
- First Published May 8, 2017
Research
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy
- First Published May 2, 2017
Research
Gene flow, ancient polymorphism, and ecological adaptation shape the genomic landscape of divergence among Darwin's finches
- First Published April 25, 2017
Method
Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes
- First Published April 19, 2017
Research
Drosophila housekeeping promoters facilitates their expression" > Clustering of Drosophila housekeeping promoters facilitates their expression
- First Published April 18, 2017
Resource
Identification of protein features encoded by alternative exons using Exon Ontology
- First Published April 18, 2017
Method
Plasmodium falciparum" > Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum
- First Published April 17, 2017
Research
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
- First Published April 14, 2017
Method
Extending the spectrum of DNA sequences retrieved from ancient bones and teeth
- First Published April 13, 2017
Research
Accumulation of RNA on chromatin disrupts heterochromatic silencing
- First Published April 12, 2017
Method
Increased taxon sampling reveals thousands of hidden orthologs in flatworms
- First Published April 11, 2017
Resource
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly
- First Published April 10, 2017
Research
Cytosine modifications modulate the chromatin architecture of transcriptional enhancers
- First Published April 10, 2017
Method
Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci
- First Published April 6, 2017
Research
Asian wild rice is a hybrid swarm with extensive gene flow and feralization from domesticated rice
- First Published April 6, 2017
Research
Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha
- First Published April 6, 2017
Research
Arabidopsis genome at the nuclear periphery" > Nonrandom domain organization of the Arabidopsis genome at the nuclear periphery
- First Published April 6, 2017