Your search for returned 6,372 results
Research
Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains
- First Published May 30, 2018
Research
Inherited DNA methylation primes the establishment of accessible chromatin during genome activation
- First Published May 29, 2018
Research
Evaluating recovery potential of the northern white rhinoceros from cryopreserved somatic cells
- First Published May 24, 2018
Method
Detecting, quantifying, and discriminating the mechanism of mosaic chromosomal aneuploidies using MAD-seq
- First Published May 17, 2018
Method
Modeling leaderless transcription and atypical genes results in more accurate gene prediction in prokaryotes
- First Published May 17, 2018
Method
Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing
- First Published May 15, 2018
Method
Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations
- First Published May 11, 2018
Research
Allele-specific control of replication timing and genome organization during development
- First Published May 7, 2018
Research
The peopling of South America and the trans-Andean gene flow of the first settlers
- First Published May 7, 2018
Method
Detection and analysis of ancient segmental duplications in mammalian genomes
- First Published May 7, 2018
Research
A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells
- First Published May 4, 2018
Research
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
- First Published May 4, 2018
Corrigendum
Corrigendum: Evolutionary expansion of DNA hypomethylation in the mammalian germline genome
- First Published May 1, 2018
Corrigendum
Corrigendum: Detecting differential copy number variation between groups of samples
- First Published May 1, 2018
Corrigendum
Corrigendum: A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity
- First Published May 1, 2018
Research
Birth, evolution, and transmission of satellite-free mammalian centromeric domains
- First Published April 30, 2018
Research
Molecular dissection of a natural transposable element invasion
- First Published April 30, 2018
Method
Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection
- First Published April 30, 2018
Resource
A comparative transcriptional landscape of maize and sorghum obtained by single-molecule sequencing
- First Published April 30, 2018
Method
Comprehensive viral enrichment enables sensitive respiratory virus genomic identification and analysis by next generation sequencing
- First Published April 27, 2018
Resource
Hackathons as a means of accelerating scientific discoveries and knowledge transfer
- First Published April 12, 2018
Research
Enduring epigenetic landmarks define the cancer microenvironment
- First Published April 12, 2018
Research
HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo
- First Published April 12, 2018
Research
In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors
- First Published April 11, 2018
Research
L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis
- First Published April 11, 2018
Research
C. elegans and human cancers" > Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers
- First Published April 10, 2018
Research
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
- First Published April 9, 2018
Perspective
Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship
- First Published April 6, 2018
Research
Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome
- First Published April 4, 2018
Method
Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer
- First Published April 4, 2018
Corrigendum
Corrigendum: Direct determination of diploid genome sequences
- First Published April 2, 2018
Corrigendum
Corrigendum: Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast
- First Published April 2, 2018
Editorial
A statement about the publication describing genome sequencing of the Atacama skeleton
- First Published March 30, 2018
Method
taxMaps: comprehensive and highly accurate taxonomic classification of short-read data in reasonable time
- First Published March 27, 2018
Method
Sequential regulatory activity prediction across chromosomes with convolutional neural networks
- First Published March 27, 2018
Method
Double insertion of transposable elements provides a substrate for the evolution of satellite DNA
- First Published March 27, 2018
Method
Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo
- First Published March 23, 2018
Research
Promoter architecture determines cotranslational regulation of mRNA
- First Published March 22, 2018
Research
Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia
- First Published March 22, 2018
Research
Mus caroli and Mus pahari genomes" > Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes
- First Published March 21, 2018
Research
Genome-wide determinants of sequence-specific DNA binding of general regulatory factors
- First Published March 21, 2018
Research
Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
- First Published March 16, 2018
Method
SvABA: genome-wide detection of structural variants and indels by local assembly
- First Published March 13, 2018
Research
Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals
- First Published March 2, 2018
Research
Intrinsic DNA binding properties demonstrated for lineage-specifying basic helix-loop-helix transcription factors
- First Published March 2, 2018
Method
Genome-reconstruction for eukaryotes from complex natural microbial communities
- First Published March 1, 2018
Research
Selective maternal seeding and environment shape the human gut microbiome
- First Published March 1, 2018
Research
Conserved microRNA targeting reveals preexisting gene dosage sensitivities that shaped amniote sex chromosome evolution
- First Published February 15, 2018
Research
Enhancer RNA profiling predicts transcription factor activity
- First Published February 15, 2018
Research
Widespread and precise reprogramming of yeast protein–genome interactions in response to heat shock
- First Published February 14, 2018
Method
FIND: difFerential chromatin INteractions Detection using a spatial Poisson process
- First Published February 12, 2018
Research
3′ UTR lengthening as a novel mechanism in regulating cellular senescence
- First Published February 12, 2018
Method
SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification
- First Published February 9, 2018
Research
ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters
- First Published February 2, 2018
Research
Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures
- First Published February 2, 2018
Research
Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control
- First Published January 24, 2018
Method
KRAS with CRISPR-Cas9 controls tumor growth" > Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth
- First Published January 11, 2018
Research
Relationship between histone modifications and transcription factor binding is protein family specific
- First Published January 11, 2018
Method
Reconstructing differentiation networks and their regulation from time series single-cell expression data
- First Published January 9, 2018
Research
cis-regulatory activity" > Local sequence features that influence AP-1 cis-regulatory activity
- First Published January 5, 2018
Corrigendum
Corrigendum: Discovery and genotyping of structural variation from long-read haploid genome sequence data
- First Published January 2, 2018
Method
Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair
- First Published December 22, 2017
Research
Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis
- First Published December 22, 2017
Research
The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes
- First Published December 22, 2017
Method
Caenorhabditis elegans reference genome" > MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome
- First Published December 22, 2017
Research
Evolutionary expansion of DNA hypomethylation in the mammalian germline genome
- First Published December 19, 2017
Research
Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast
- First Published December 18, 2017
Research
Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs
- First Published December 18, 2017
Research
Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data
- First Published December 18, 2017
Research
Saturation mutagenesis reveals manifold determinants of exon definition
- First Published December 14, 2017
Research
Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection
- First Published December 13, 2017
Resource
The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting
- First Published December 12, 2017
Research
Drosophila genus" > Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus
- First Published December 12, 2017
Research
DNA mismatch repair preferentially protects genes from mutation
- First Published December 12, 2017
Method
Integrated analysis of motif activity and gene expression changes of transcription factors
- First Published December 12, 2017
Research
H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2
- First Published December 11, 2017
Method
Detecting differential copy number variation between groups of samples
- First Published December 11, 2017
Method
Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI
- First Published December 8, 2017
Method
SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells
- First Published December 5, 2017
Resource
Impact of regulatory variation across human iPSCs and differentiated cells
- First Published December 5, 2017
Method
SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site
- First Published December 1, 2017
Method
Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome
- First Published December 1, 2017
Corrigendum
Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal
- First Published December 1, 2017
Research
Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini
- First Published November 21, 2017
Method
Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing
- First Published November 16, 2017
Method
An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics
- First Published November 15, 2017
Resource
C. elegans" > Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans
- First Published November 15, 2017