Your search for returned 6,372 results
Research
Nucleosome remodeling at origins of global genome–nucleotide excision repair occurs at the boundaries of higher-order chromatin structure
- First Published December 14, 2018
Research
Hormone-control regions mediate steroid receptor–dependent genome organization
- First Published December 14, 2018
Research
A quantitative framework for characterizing the evolutionary history of mammalian gene expression
- First Published December 14, 2018
Research
Transposable element insertions in fission yeast drive adaptation to environmental stress
- First Published December 12, 2018
Research
Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock
- First Published December 6, 2018
Method
Minerva: an alignment- and reference-free approach to deconvolve Linked-Reads for metagenomics
- First Published December 6, 2018
Resource
Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees
- First Published December 4, 2018
Research
Accelerated rates of large-scale mutations in the presence of copper and nickel
- First Published November 28, 2018
Research
Drosophila regeneration" > Damage-responsive elements in Drosophila regeneration
- First Published November 20, 2018
Method
Quantification of somatic mutation flow across individual cell division events by lineage sequencing
- First Published November 20, 2018
Research
Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions
- First Published November 19, 2018
Method
DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA
- First Published November 9, 2018
Method
Defining TP53 pioneering capabilities with competitive nucleosome binding assays
- First Published November 8, 2018
Method
HD-Marker: a highly multiplexed and flexible approach for targeted genotyping of more than 10,000 genes in a single-tube assay
- First Published November 8, 2018
Method
SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA
- First Published November 7, 2018
Research
Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate
- First Published November 6, 2018
Research
Noncoding transcription influences the replication initiation program through chromatin regulation
- First Published November 6, 2018
Corrigendum
Drosophila" > Corrigendum: Tempo and mode of regulatory evolution in Drosophila
- First Published November 1, 2018
Research
Evolutionary conservation of Y Chromosome ampliconic gene families despite extensive structural variation
- First Published October 31, 2018
Research
LTRs activated by Epstein-Barr virus–induced transformation of B cells alter the transcriptome
- First Published October 31, 2018
Research
Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes
- First Published October 24, 2018
Research
Expanding heterochromatin reveals discrete subtelomeric domains delimited by chromatin landscape transitions
- First Published October 24, 2018
Method
NanoPARE: parallel analysis of RNA 5′ ends from low-input RNA
- First Published October 24, 2018
Research
Ranking noncanonical 5′ splice site usage by genome-wide RNA-seq analysis and splicing reporter assays
- First Published October 24, 2018
Research
Global transcriptional activity dynamics reveal functional enhancer RNAs
- First Published October 23, 2018
Research
Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians
- First Published October 23, 2018
Method
Targeted genotyping of variable number tandem repeats with adVNTR
- First Published October 23, 2018
Research
PRDM9 expression impacts the pan-cancer genomic landscape" > Aberrant PRDM9 expression impacts the pan-cancer genomic landscape
- First Published October 19, 2018
Method
Chromosome assembly of large and complex genomes using multiple references
- First Published October 19, 2018
Resource
Maftools: efficient and comprehensive analysis of somatic variants in cancer
- First Published October 19, 2018
Research
Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes
- First Published October 17, 2018
Method
High-salt–recovered sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies
- First Published October 4, 2018
Research
Drosophila" > Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila
- First Published October 2, 2018
Research
The gene repressor complex NuRD interacts with the histone variant H3.3 at promoters of active genes
- First Published September 25, 2018
Method
High-throughput characterization of genetic effects on DNA–protein binding and gene transcription
- First Published September 25, 2018
Resource
The genomic architecture and molecular evolution of ant odorant receptors
- First Published September 24, 2018
Research
Metagenomic analysis with strain-level resolution reveals fine-scale variation in the human pregnancy microbiome
- First Published September 19, 2018
Research
Young genes have distinct gene structure, epigenetic profiles, and transcriptional regulation
- First Published September 19, 2018
Research
Pristionchus nematodes" > Deep taxon sampling reveals the evolutionary dynamics of novel gene families in Pristionchus nematodes
- First Published September 19, 2018
Research
Crosstalk between alternative polyadenylation and miRNAs in the regulation of protein translational efficiency
- First Published September 18, 2018
Method
Transcriptional fates of human-specific segmental duplications in brain
- First Published September 18, 2018
Research
Gene regulation underlies environmental adaptation in house mice
- First Published September 7, 2018
Corrigendum
Corrigendum: Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks
- First Published September 4, 2018
Research
Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)
- First Published August 31, 2018
Research
Coregulation of ribosomal RNA with hundreds of genes contributes to phenotypic variation
- First Published August 30, 2018
Research
Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns
- First Published August 30, 2018
Research
A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo
- First Published August 29, 2018
Research
Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes
- First Published August 28, 2018
Research
Single-cell RNA-sequencing reveals the existence of naive and primed pluripotency in pre-implantation rhesus monkey embryos
- First Published August 28, 2018
Research
Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells
- First Published August 24, 2018
Research
A compendium of conserved cleavage and polyadenylation events in mammalian genes
- First Published August 24, 2018
Research
Exonic splice regulation imposes strong selection at synonymous sites
- First Published August 24, 2018
Research
Phenotypically distinct female castes in honey bees are defined by alternative chromatin states during larval development
- First Published August 22, 2018
Research
C. elegans identified genomic loci controlling metabolite levels" > Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels
- First Published August 14, 2018
Research
Noncanonical secondary structures arising from non-B DNA motifs are determinants of mutagenesis
- First Published August 13, 2018
Research
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding
- First Published August 10, 2018
Method
Whole-genome bisulfite sequencing with improved accuracy and cost
- First Published August 9, 2018
Method
High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics
- First Published August 7, 2018
Perspective
Realizing the potential of blockchain technologies in genomics
- First Published August 3, 2018
Research
Tracing human stem cell lineage during development using DNA methylation
- First Published August 2, 2018
Corrigendum
Plasmodium falciparum" > Corrigendum: Interactive transcriptome analysis of malaria patients and infecting Plasmodium falciparum
- First Published August 1, 2018
Method
Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations
- First Published July 30, 2018
Resource
High resolution annotation of zebrafish transcriptome using long-read sequencing
- First Published July 30, 2018
Method
GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens
- First Published July 26, 2018
Research
Drosophila via gradual loss of fitness advantages" > Death of new microRNA genes in Drosophila via gradual loss of fitness advantages
- First Published July 26, 2018
Research
cis-acting splicing-associated variants in human cancer" > A comprehensive characterization of cis-acting splicing-associated variants in human cancer
- First Published July 16, 2018
Method
Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data using universal protein motifs" > Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data using universal protein motifs
- First Published July 13, 2018
Research
Plant 24-nt reproductive phasiRNAs from intramolecular duplex mRNAs in diverse monocots
- First Published July 12, 2018
Research
A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization
- First Published July 12, 2018
Research
Arabidopsis thaliana" > Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana
- First Published July 3, 2018
Research
Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retroviruses
- First Published July 3, 2018
Research
Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers
- First Published July 3, 2018
Corrigendum
Corrigendum: SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification
- First Published July 2, 2018
Research
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line
- First Published June 28, 2018
Research
The organization of genome duplication is a critical determinant of the landscape of genome maintenance
- First Published June 22, 2018
Method
Genome-scale identification of cellular pathways required for cell surface recognition
- First Published June 18, 2018
Research
Epigenetic maintenance of topological domains in the highly rearranged gibbon genome
- First Published June 18, 2018
Method
Alu/Alu-mediated rearrangements" > Predicting human genes susceptible to genomic instability associated with Alu/Alu-mediated rearrangements
- First Published June 15, 2018
Method
A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs
- First Published June 15, 2018
Resource
EPIGEN-Brazil Initiative resources: a Latin American imputation panel and the Scientific Workflow
- First Published June 14, 2018
Research
Long-read sequencing of nascent RNA reveals coupling among RNA processing events
- First Published June 14, 2018
Research
Human primitive brain displays negative mitochondrial-nuclear expression correlation of respiratory genes
- First Published June 14, 2018
Research
Parent-of-origin-dependent nucleosome organization correlates with genomic imprinting in maize
- First Published June 14, 2018
Research
Human-specific features of spatial gene expression and regulation in eight brain regions
- First Published June 13, 2018
Method
Principled multi-omic analysis reveals gene regulatory mechanisms of phenotype variation
- First Published June 13, 2018
Method
Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data
- First Published June 13, 2018
Method
Comparative Annotation Toolkit (CAT)—simultaneous clade and personal genome annotation
- First Published June 8, 2018
Research
A model for postzygotic mosaicisms quantifies the allele fraction drift, mutation rate, and contribution to de novo mutations
- First Published June 6, 2018
Research
Human long intrinsically disordered protein regions are frequent targets of positive selection
- First Published June 1, 2018
Research
Base-specific mutational intolerance near splice sites clarifies the role of nonessential splice nucleotides
- First Published June 1, 2018
