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Research

cis-regulatory variation modifies the penetrance of pathogenic SHROOM3 variants in craniofacial microsomia" > Common cis-regulatory variation modifies the penetrance of pathogenic SHROOM3 variants in craniofacial microsomia

  • First Published April 15, 2025
Perspective

Short arms of human acrocentric chromosomes and the completion of the human genome sequence

  • First Published March 31, 2022
In memoriam

Haig H. Kazazian, Jr. (1937–2022)

  • First Published March 21, 2022
Research

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes

  • First Published October 24, 2018
Research

Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection

  • First Published December 13, 2017
Research

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

  • First Published January 11, 2016
Research

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

  • First Published April 27, 2015
Resource

Simultaneous identification and prioritization of variants in familial, de novo, and somatic genetic disorders with VariantMaster

  • First Published January 3, 2014
Research

The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome

  • First Published June 19, 2013
Resource

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

  • First Published May 28, 2013
Research

A functional methylome map of ulcerative colitis

  • First Published July 23, 2012
Research

DNA methylation profiles of human active and inactive X chromosomes

  • First Published August 23, 2011
Research

Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors

  • First Published February 1, 2011
Research

cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts" > Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts

  • First Published December 8, 2010
Method

Methylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15

  • First Published July 14, 2010
Research

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

  • First Published March 10, 2010
Methods

Transcriptional and post-transcriptional profile of human chromosome 21

  • First Published July 6, 2009
LETTER

Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex

  • First Published October 10, 2008
RESOURCE

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

  • First Published June 24, 2008
RESOURCE

Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21

  • First Published September 25, 2007
ARTICLE

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
LETTER

Pseudogenes in the ENCODE regions: Consensus annotation, analysis of transcription, and evolution

  • First Published June 13, 2007
LETTER

Structured RNAs in the ENCODE selected regions of the human genome

  • First Published June 13, 2007
LETTER

Tandem chimerism as a means to increase protein complexity in the human genome

  • First Published December 12, 2005
LETTER

KIR) loci in primates" > Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates

  • First Published January 3, 2005
LETTER

Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome

  • First Published July 1, 2004
RESOURCE

Complete MHC Haplotype Sequencing for Common Disease Gene Mapping

  • First Published May 12, 2004
LETTER

Comparison of Human Chromosome 21 Conserved Nongenic Sequences (CNGs) With the Mouse and Dog Genomes Shows That Their Selective Constraint Is Independent of Their Genic Environment

  • First Published April 12, 2004
REPORT

Characterization of Clustered MHC-Linked Olfactory Receptor Genes in Human and Mouse

  • First Published March 13, 2001
RESOURCE

A cSNP Map and Database for Human Chromosome 21

  • First Published January 18, 2001
LETTER

MHC-Linked Olfactory Receptor Loci Exhibit Polymorphism and Contribute to Extended HLA/OR-Haplotypes

  • First Published December 1, 2000
LETTER

The Mouse Brain Transcriptome by SAGE: Differences in Gene Expression between P30 Brains of the Partial Trisomy 16 Mouse Model of Down Syndrome (Ts65Dn) and Normals

  • First Published December 1, 2000
ARTICLE

Patterns of Meiotic Recombination on the Long Arm of Human Chromosome 21

  • First Published September 1, 2000
LETTER

Construction of a High-Resolution 2.5-Mb Transcript Map of the Human 6p21.2–6p21.3 Region Immediately Centromeric of the Major Histocompatibility Complex

  • First Published April 1, 2000
LETTER

A High-Resolution Physical Map of Human Chromosome 21p Using Yeast Artificial Chromosomes

  • First Published November 1, 1999
RESEARCH

Estimation of Distances and Map Construction Using Radiation Hybrids

  • First Published May 1, 1998
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