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Research

Gaps and complex structurally variant loci in phased genome assemblies

  • First Published May 10, 2023
Research

Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera

  • First Published December 8, 2022
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages" > Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages

  • First Published November 18, 2020
Research

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

  • First Published August 20, 2020
Resource

A chromosome-level assembly of the Atlantic herring genome—detection of a supergene and other signals of selection

  • First Published October 24, 2019
Method

Chromosome assembly of large and complex genomes using multiple references

  • First Published October 19, 2018
Research

Mus caroli and Mus pahari genomes" > Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes

  • First Published March 21, 2018
Corrigendum

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

  • First Published December 1, 2017
Method

cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis" > Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis

  • First Published October 11, 2017
Method

Co-expression networks reveal the tissue-specific regulation of transcription and splicing

  • First Published October 11, 2017
Resource

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

  • First Published April 10, 2017
Corrigendum

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

  • First Published November 1, 2016
Research

Macaca mulatta) based on whole-genome sequences" > The population genomics of rhesus macaques (Macaca mulatta) based on whole-genome sequences

  • First Published October 17, 2016
Research

Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young

  • First Published July 19, 2016
Insight/Outlook

The ethics of conducting molecular autopsies in cases of sudden death in the young

  • First Published July 13, 2016
Research

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

  • First Published February 12, 2015
Research

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

  • First Published February 2, 2015
Research

Decoupling of evolutionary changes in transcription factor binding and gene expression in mammals

  • First Published November 13, 2014
Research

Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

  • First Published October 7, 2014
Research

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

  • First Published September 16, 2014
Resource

D. melanogaster modENCODE transcriptome annotation" > Comparative validation of the D. melanogaster modENCODE transcriptome annotation

  • First Published July 1, 2014
Resource

Drosophila melanogaster Genetic Reference Panel lines" > Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

  • First Published April 8, 2014
Research

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

  • First Published September 3, 2013
Method

An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data

  • First Published January 7, 2013
Research

cis-trans regulation in the evolution of mouse gene expression" > Extensive compensatory cis-trans regulation in the evolution of mouse gene expression

  • First Published August 23, 2012
Research

cis-regulatory modules" > Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

  • First Published July 10, 2012
Resource

Strongylocentrotus purpuratus based on transcriptome analysis" > Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis

  • First Published June 18, 2012
Research

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance

  • First Published April 29, 2010
Research

A CTCF-independent role for cohesin in tissue-specific transcription

  • First Published March 10, 2010
Resource

A SNP discovery method to assess variant allele probability from next-generation resequencing data

  • First Published December 17, 2009
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Letter

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

  • First Published April 28, 2009
LETTER

A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome

  • First Published December 3, 2008
Methods

Genome-wide nucleotide-level mammalian ancestor reconstruction

  • First Published October 10, 2008
LETTER

Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5′-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes

  • First Published July 9, 2008
RESOURCE

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

  • First Published June 24, 2008
LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008
RESOURCE

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser

  • First Published November 5, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
ARTICLE

The landscape of histone modifications across 1% of the human genome in five human cell lines

  • First Published June 13, 2007
COMMENTARY

Community annotation: Procedures, protocols, and supporting tools

  • First Published October 25, 2006
LETTER

Phylogenomic analysis reveals bees and wasps (Hymenoptera) at the base of the radiation of Holometabolous insects

  • First Published October 25, 2006
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
Methods

Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay

  • First Published February 1, 2005
Methods

Pooled genomic indexing of rhesus macaque

  • First Published February 1, 2005
ARTICLE

Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution" > Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

  • First Published January 3, 2005
RESOURCE

The Atlas Genome Assembly System

  • First Published April 1, 2004
LETTER

Genomic Analysis of the Nuclear Receptor Family: New Insights Into Structure, Regulation, and Evolution From the Rat Genome

  • First Published April 1, 2004
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