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Method

Genome-wide maps of CPD deamination in yeast reveal the impact of DNA sequence context and nucleosome architecture on cytosine deamination rates

  • Marian F. Laughery
  • Bastian Stark
  • Benjamin Morledge-Hampton
  • Steven A. Roberts
  • John J. Wyrick
  • First Published December 9, 2025
Method

Multicondition and multimodal temporal profile inference during mouse embryonic development

  • Ran Zhang
  • Chengxiang Qiu
  • Galina N. Filippova
  • Gang Li
  • Jay Shendure
  • Jean-Philippe Vert
  • Xinxian Deng
  • William Stafford Noble
  • Christine M. Disteche
  • First Published August 14, 2025
Research

Genetic inhibitors of APOBEC3B-induced mutagenesis

  • Tony M. Mertz
  • Elizabeth Rice-Reynolds
  • Ly Nguyen
  • Anna Wood
  • Cameron Cordero
  • Nicholas Bray Victoria Harcy
  • ... [+2 authors] ...,
  • Rudri K. Vyas
  • Debra Mitchell
  • Kirill Lobachev
  • Steven A. Roberts
  • First Published August 2, 2023
Resource

Caenorhabditis elegans nematodes" > Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes

  • Timothy J. Durham
  • Riza M. Daza
  • Louis Gevirtzman
  • Darren A. Cusanovich
  • Olubusayo Bolonduro
  • William Stafford Noble
  • Jay Shendure
  • Robert H. Waterston
  • First Published April 22, 2021
Research

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

  • Brian S. Roberts
  • E. Christopher Partridge
  • Bryan A. Moyers
  • Vikram Agarwal
  • Kimberly M. Newberry
  • Beth K. Martin
  • Jay Shendure
  • Richard M. Myers
  • Gregory M. Cooper
  • First Published April 20, 2021
Research

Mecp2-null mice implicate the DNA damage response in Rett syndrome pathology" > Suppressor mutations in Mecp2-null mice implicate the DNA damage response in Rett syndrome pathology

  • Adebola Enikanolaiye
  • Julie Ruston
  • Rong Zeng
  • Christine Taylor
  • Marijke Schrock
  • Christie M. Buchovecky
  • Jay Shendure
  • Elif Acar
  • Monica J. Justice
  • First Published April 21, 2020
Research

Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in skin cancer

  • Peng Mao
  • Michael J. Smerdon
  • Steven A. Roberts
  • John J. Wyrick
  • First Published December 23, 2019
Research

Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity

  • Peng Mao
  • Alexander J. Brown
  • Ewa P. Malc
  • Piotr A. Mieczkowski
  • Michael J. Smerdon
  • Steven A. Roberts
  • John J. Wyrick
  • First Published September 14, 2017
Research

A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity

  • Fumitaka Inoue
  • Martin Kircher
  • Beth Martin
  • Gregory M. Cooper
  • Daniela M. Witten
  • Michael T. McManus
  • Nadav Ahituv
  • Jay Shendure
  • First Published November 9, 2016
Corrigendum

Corrigendum: MIPSTR: a method for multiplex genotyping of germline and somatic STR variation across many individuals

  • Keisha D. Carlson
  • Peter H. Sudmant
  • Maximilian O. Press
  • Evan E. Eichler
  • Jay Shendure
  • Christine Queitsch
  • First Published August 3, 2015
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