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Method

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

  • Jonathan S. Brammeld
  • Mia Petljak
  • Inigo Martincorena
  • Steven P. Williams
  • Luz Garcia Alonso
  • Alba Dalmases Beatriz Bellosillo Carla Daniela Robles-Espinoza Stacey Price Syd Barthorpe Patrick Tarpey Constantine Alifrangis Graham Bignell Joana Vidal Jamie Young Lucy Stebbings Kathryn Beal Michael R. Stratton Julio Saez-Rodriguez
  • ... [+14 authors] ...,
  • Mathew Garnett
  • Clara Montagut
  • Francesco Iorio
  • Ultan McDermott
  • First Published February 8, 2017
Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • Young Seok Ju
  • Jose M.C. Tubio
  • William Mifsud
  • Beiyuan Fu
  • Helen R. Davies
  • Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
  • ... [+39 authors] ...,
  • Fengtang Yang
  • Serena Nik-Zainal
  • Peter J. Campbell
  • Michael R. Stratton
  • First Published May 2, 2016
Research

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • Young Seok Ju
  • Jose M.C. Tubio
  • William Mifsud
  • Beiyuan Fu
  • Helen R. Davies
  • Manasa Ramakrishna Yilong Li Lucy Yates Gunes Gundem Patrick S. Tarpey Sam Behjati Elli Papaemmanuil Sancha Martin Anthony Fullam Moritz Gerstung Jyoti Nangalia Anthony R. Green Carlos Caldas Åke Borg Andrew Tutt Ming Ta Michael Lee Laura J. van't Veer Benita K.T. Tan Samuel Aparicio Paul N. Span John W.M. Martens Stian Knappskog Anne Vincent-Salomon Anne-Lise Børresen-Dale Jórunn Erla Eyfjörd Ola Myklebost Adrienne M. Flanagan Christopher Foster David E. Neal Colin Cooper Rosalind Eeles G. Steven Bova Sunil R. Lakhani Christine Desmedt Gilles Thomas Andrea L. Richardson Colin A. Purdie Alastair M. Thompson Ultan McDermott
  • ... [+39 authors] ...,
  • Fengtang Yang
  • Serena Nik-Zainal
  • Peter J. Campbell
  • Michael R. Stratton
  • First Published May 11, 2015
Research

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency" > C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

  • Bettina Meier
  • Susanna L. Cooke
  • Joerg Weiss
  • Aymeric P. Bailly
  • Ludmil B. Alexandrov
  • John Marshall Keiran Raine Mark Maddison
  • ... [+3 authors] ...,
  • Elizabeth Anderson
  • Michael R. Stratton
  • Anton Gartner
  • Peter J. Campbell
  • First Published July 16, 2014
Method

Estimation of rearrangement phylogeny for cancer genomes

  • Chris D. Greenman
  • Erin D. Pleasance
  • Scott Newman
  • Fengtang Yang
  • Beiyuan Fu
  • Serena Nik-Zainal David Jones King Wai Lau Nigel Carter
  • ... [+4 authors] ...,
  • Paul A.W. Edwards
  • P. Andrew Futreal
  • Michael R. Stratton
  • Peter J. Campbell
  • First Published October 12, 2011
Method

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

  • Lukas Chavez
  • Justyna Jozefczuk
  • Christina Grimm
  • Jörn Dietrich
  • Bernd Timmermann
  • Hans Lehrach
  • Ralf Herwig
  • James Adjaye
  • First Published August 27, 2010
Letter

Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention

  • Andrew L. Hufton
  • Susanne Mathia
  • Helene Braun
  • Udo Georgi
  • Hans Lehrach
  • Martin Vingron
  • Albert J. Poustka
  • Georgia Panopoulou
  • First Published August 24, 2009
LETTER

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement

  • Andrew L. Hufton
  • Detlef Groth
  • Martin Vingron
  • Hans Lehrach
  • Albert J. Poustka
  • Georgia Panopoulou
  • First Published July 14, 2008
LETTER

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

  • Graham R. Bignell
  • Thomas Santarius
  • Jessica C.M. Pole
  • Adam P. Butler
  • Janet Perry
  • Erin Pleasance Chris Greenman Andrew Menzies Sheila Taylor Sarah Edkins Peter Campbell Michael Quail Bob Plumb Lucy Matthews Kirsten McLay Paul A.W. Edwards
  • ... [+11 authors] ...,
  • Jane Rogers
  • Richard Wooster
  • P. Andrew Futreal
  • Michael R. Stratton
  • First Published August 3, 2007
Methods

Decoding the fine-scale structure of a breast cancer genome and transcriptome

  • Stanislav Volik
  • Benjamin J. Raphael
  • Guiqing Huang
  • Michael R. Stratton
  • Graham Bignel
  • John Murnane John H. Brebner Krystyna Bajsarowicz Pamela L. Paris Quanzhou Tao David Kowbel Anna Lapuk Dmitri A. Shagin Irina A. Shagina Joe W. Gray
  • ... [+10 authors] ...,
  • Jan-Fang Cheng
  • Pieter J. de Jong
  • Pavel Pevzner
  • Colin Collins
  • First Published February 3, 2006
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