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Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • Myungjin Jo
  • Ah Young Chung
  • Nozomu Yachie
  • Minchul Seo
  • Hyejin Jeon
  • Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
  • ... [+4 authors] ...,
  • Marc Vidal
  • Hae Chul Park
  • Frederick P. Roth
  • Kyoungho Suk
  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • Song Sun
  • Fan Yang
  • Guihong Tan
  • Michael Costanzo
  • Rose Oughtred
  • Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
  • ... [+10 authors] ...,
  • Brenda J. Andrews
  • Charles Boone
  • Kara Dolinski
  • Frederick P. Roth
  • First Published March 14, 2016
Method

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

  • Lukas Chavez
  • Justyna Jozefczuk
  • Christina Grimm
  • Jörn Dietrich
  • Bernd Timmermann
  • Hans Lehrach
  • Ralf Herwig
  • James Adjaye
  • First Published August 27, 2010
Resource

Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • Kourosh Salehi-Ashtiani
  • Chenwei Lin
  • Tong Hao
  • Yun Shen
  • David Szeto
  • Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
  • ... [+7 authors] ...,
  • Michael E. Cusick
  • Frederick P. Roth
  • David E. Hill
  • Marc Vidal
  • First Published October 2, 2009
Letter

Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention

  • Andrew L. Hufton
  • Susanne Mathia
  • Helene Braun
  • Udo Georgi
  • Hans Lehrach
  • Martin Vingron
  • Albert J. Poustka
  • Georgia Panopoulou
  • First Published August 24, 2009
Methods

Quantitative phenotyping via deep barcode sequencing

  • Andrew M. Smith
  • Lawrence E. Heisler
  • Joseph Mellor
  • Fiona Kaper
  • Michael J. Thompson
  • Mark Chee
  • Frederick P. Roth
  • Guri Giaever
  • Corey Nislow
  • First Published July 21, 2009
LETTER

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement

  • Andrew L. Hufton
  • Detlef Groth
  • Martin Vingron
  • Hans Lehrach
  • Albert J. Poustka
  • Georgia Panopoulou
  • First Published July 14, 2008
RESOURCE

Versatile Gene-Specific Sequence Tags for Arabidopsis Functional Genomics: Transcript Profiling and Reverse Genetics Applications

  • Pierre Hilson
  • Joke Allemeersch
  • Thomas Altmann
  • Sébastien Aubourg
  • Alexandra Avon
  • Jim Beynon Rishikesh P. Bhalerao Frédérique Bitton Michel Caboche Bernard Cannoot Vasil Chardakov Cécile Cognet-Holliger Vincent Colot Mark Crowe Caroline Darimont Steffen Durinck Holger Eickhoff Andéol Falcon de Longevialle Edward E. Farmer Murray Grant Martin T.R. Kuiper Hans Lehrach Céline Léon Antonio Leyva Joakim Lundeberg Claire Lurin Yves Moreau Wilfried Nietfeld Javier Paz-Ares Philippe Reymond Pierre Rouzé Goran Sandberg Maria Dolores Segura Carine Serizet Alexandra Tabrett Ludivine Taconnat Vincent Thareau Paul Van Hummelen Steven Vercruysse Marnik Vuylsteke Magdalena Weingartner Peter J. Weisbeek
  • ... [+37 authors] ...,
  • Valtteri Wirta
  • Floyd R.A. Wittink
  • Marc Zabeau
  • Ian Small
  • First Published October 15, 2004
LETTER

Transcript Level Alterations Reflect Gene Dosage Effects Across Multiple Tissues in a Mouse Model of Down Syndrome

  • Pascal Kahlem
  • Marc Sultan
  • Ralf Herwig
  • Matthias Steinfath
  • Daniela Balzereit
  • Barbara Eppens Nidhi G. Saran Mathew T. Pletcher Sarah T. South
  • ... [+4 authors] ...,
  • Gail Stetten
  • Hans Lehrach
  • Roger H. Reeves
  • Marie-Laure Yaspo
  • First Published July 1, 2004
Methods

Predicting Protein Complex Membership Using Probabilistic Network Reliability

  • Saurabh Asthana
  • Oliver D. King
  • Francis D. Gibbons
  • Frederick P. Roth
  • First Published May 12, 2004
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