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In memoriam

Jim Watson (1928–2025): a genomics visionary

  • First Published July 23, 2026
Research

Comprehensive functional annotation of ESR1-driven enhancers in breast cancer reveals hierarchical activity independent of genomic and epigenomic contexts

  • First Published June 10, 2025
Resource

Allele-specific transcription factor binding across human brain regions offers mechanistic insight into eQTLs

  • First Published August 16, 2024
Research

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions

  • First Published May 6, 2024
Research

Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells

  • First Published October 18, 2023
Method

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

  • First Published July 11, 2023
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome

  • First Published June 29, 2021
Research

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

  • First Published April 20, 2021
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