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In memoriam

Jim Watson (1928–2025): a genomics visionary

  • First Published July 23, 2026
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

  • First Published July 27, 2011
Method

Genome-wide identification of conserved regulatory function in diverged sequences

  • First Published May 31, 2011
Research

XIST locus" > Comparative analysis of the primate X-inactivation center region and reconstruction of the ancestral primate XIST locus

  • First Published April 25, 2011
Method

Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing

  • First Published September 1, 2010
Article

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

  • First Published November 3, 2009
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Resource

The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine

  • First Published July 14, 2009
LETTER

Thylacinus cynocephalus)" > The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus)

  • First Published January 12, 2009
LETTER

Comparative sequence analysis of primate subtelomeres originating from a chromosome fission event

  • First Published October 24, 2008
LETTER

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

  • First Published September 25, 2008
RESOURCE

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser

  • First Published November 5, 2007
LETTER

cis-regulatory elements using comparative genomics: Some lessons from ENCODE data" > Finding cis-regulatory elements using comparative genomics: Some lessons from ENCODE data

  • First Published June 13, 2007
RESOURCE

A framework for collaborative analysis of ENCODE data: Making large-scale analyses biologist-friendly

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
LETTER

Using genomic data to unravel the root of the placental mammal phylogeny

  • First Published February 23, 2007
Methods

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements

  • First Published October 19, 2006
LETTER

cis-regulatory modules" > Experimental validation of predicted mammalian erythroid cis-regulatory modules

  • First Published October 12, 2006
Methods

Reconstructing contiguous regions of an ancestral genome

  • First Published September 18, 2006
RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006
LETTER

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

  • First Published April 10, 2006
RESOURCE

Galaxy: A platform for interactive large-scale genome analysis

  • First Published September 16, 2005
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
ARTICLE

Distribution and intensity of constraint in mammalian genomic sequence

  • First Published June 17, 2005
Chicken Special/Resources

Mulan: Multiple-sequence local alignment and visualization for studying function and evolution

  • First Published December 8, 2004
Chicken Special/Letters

Evolution and functional classification of vertebrate gene deserts

  • First Published December 8, 2004
LETTER

Reconstructing large regions of an ancestral mammalian genome in silico

  • First Published December 1, 2004
LETTER

An intermediate grade of finished genomic sequence suitable for comparative analyses

  • First Published October 12, 2004
RESOURCE

Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner

  • First Published April 1, 2004
Methods

Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat

  • First Published April 1, 2004
LETTER

Comparative Analysis of the α-Like Globin Clusters in Mouse, Rat, and Human Chromosomes Indicates a Mechanism Underlying Breaks in Conserved Synteny

  • First Published April 1, 2004
ARTICLE

Patterns of Insertions and Their Covariation With Substitutions in the Rat, Mouse, and Human Genomes

  • First Published April 1, 2004
RESOURCE

zPicture: Dynamic Alignment and Visualization Tool for Analyzing Conservation Profiles

  • First Published March 1, 2004
ARTICLE

Identification and Characterization of Multi-Species Conserved Sequences

  • First Published December 1, 2003
LETTER

Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

  • First Published May 1, 2003
RESOURCE

GALA, a Database for Genomic Sequence Alignments and Annotations

  • First Published April 1, 2003
METHODS

LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

  • First Published March 12, 2003
LETTER

Analysis of Primate Genomic Variation Reveals a Repeat-Driven Expansion of the Human Genome

  • First Published March 1, 2003
LETTER

Distinguishing Regulatory DNA From Neutral Sites

  • First Published January 1, 2003
LETTER

Gene Length and Proximity to Neighbors Affect Genome-Wide Expression Levels

  • First Published January 1, 2003
ARTICLE

Covariation in Frequencies of Substitution, Deletion, Transposition, and Recombination During Eutherian Evolution

  • First Published January 1, 2003
METHODS

Human–Mouse Alignments with BLASTZ

  • First Published December 30, 2002
LETTER

Pericentromeric Duplications in the Laboratory Mouse

  • First Published December 30, 2002
METHODS

Parallel Construction of Orthologous Sequence-Ready Clone Contig Maps in Multiple Species

  • First Published August 1, 2002
REPORT

3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome " > Generation and Comparative Analysis of ∼3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome

  • First Published January 1, 2002
COMMENTARY

The Human Genome Sequence Expedition: Views from the “Base Camp”

  • First Published May 1, 2001
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