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Method

Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC

  • First Published April 10, 2025
Research

Sequence determinants of polyadenylation-mediated regulation

  • First Published September 17, 2019
Research

Systematic interrogation of human promoters

  • First Published January 8, 2019
Corrigendum

Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published March 1, 2017
Research

Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

  • First Published December 13, 2016
Research

Noise in gene expression is coupled to growth rate

  • First Published September 9, 2015
Corrigendum

Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site

  • First Published September 1, 2015
Research

Core promoter sequence in yeast is a major determinant of expression level

  • First Published May 12, 2015
Method

Unraveling determinants of transcription factor binding outside the core binding site

  • First Published March 11, 2015
Research

Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters

  • First Published October 7, 2014
Method

Probing the effect of promoters on noise in gene expression using thousands of designed sequences

  • First Published July 16, 2014
Resource

Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach

  • First Published August 15, 2013
Research

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

  • First Published February 12, 2013
Research

Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters

  • First Published October 18, 2011
Research

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

  • First Published July 27, 2011
Method

Genome-wide identification of conserved regulatory function in diverged sequences

  • First Published May 31, 2011
Research

C. elegans" > High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans

  • First Published December 22, 2010
Research

Overlapping codes within protein-coding sequences

  • First Published September 14, 2010
Research

p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy

  • First Published August 17, 2010
Article

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

  • First Published November 3, 2009
Methods

Incorporating nucleosomes into thermodynamic models of transcription regulation

  • First Published May 18, 2009
LETTER

Thylacinus cynocephalus)" > The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus)

  • First Published January 12, 2009
LETTER

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

  • First Published September 25, 2008
Methods

cis-regulatory motifs in human core promoters" > Systematic functional characterization of cis-regulatory motifs in human core promoters

  • First Published February 6, 2008
RESOURCE

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser

  • First Published November 5, 2007
LETTER

cis-regulatory elements using comparative genomics: Some lessons from ENCODE data" > Finding cis-regulatory elements using comparative genomics: Some lessons from ENCODE data

  • First Published June 13, 2007
RESOURCE

A framework for collaborative analysis of ENCODE data: Making large-scale analyses biologist-friendly

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
LETTER

Using genomic data to unravel the root of the placental mammal phylogeny

  • First Published February 23, 2007
Methods

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements

  • First Published October 19, 2006
LETTER

cis-regulatory modules" > Experimental validation of predicted mammalian erythroid cis-regulatory modules

  • First Published October 12, 2006
Methods

Reconstructing contiguous regions of an ancestral genome

  • First Published September 18, 2006
RESOURCE

Galaxy: A platform for interactive large-scale genome analysis

  • First Published September 16, 2005
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
Chicken Special/Resources

Mulan: Multiple-sequence local alignment and visualization for studying function and evolution

  • First Published December 8, 2004
Chicken Special/Letters

Evolution and functional classification of vertebrate gene deserts

  • First Published December 8, 2004
LETTER

Reconstructing large regions of an ancestral mammalian genome in silico

  • First Published December 1, 2004
RESOURCE

Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner

  • First Published April 1, 2004
Methods

Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat

  • First Published April 1, 2004
LETTER

Comparative Analysis of the α-Like Globin Clusters in Mouse, Rat, and Human Chromosomes Indicates a Mechanism Underlying Breaks in Conserved Synteny

  • First Published April 1, 2004
ARTICLE

Patterns of Insertions and Their Covariation With Substitutions in the Rat, Mouse, and Human Genomes

  • First Published April 1, 2004
RESOURCE

zPicture: Dynamic Alignment and Visualization Tool for Analyzing Conservation Profiles

  • First Published March 1, 2004
RESOURCE

GALA, a Database for Genomic Sequence Alignments and Annotations

  • First Published April 1, 2003
LETTER

Distinguishing Regulatory DNA From Neutral Sites

  • First Published January 1, 2003
LETTER

Gene Length and Proximity to Neighbors Affect Genome-Wide Expression Levels

  • First Published January 1, 2003
ARTICLE

Covariation in Frequencies of Substitution, Deletion, Transposition, and Recombination During Eutherian Evolution

  • First Published January 1, 2003
METHODS

Human–Mouse Alignments with BLASTZ

  • First Published December 30, 2002
REPORT

3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome " > Generation and Comparative Analysis of ∼3.3 Mb of Mouse Genomic Sequence Orthologous to the Region of Human Chromosome 7q11.23 Implicated in Williams Syndrome

  • First Published January 1, 2002
ARTICLE

Sequence and Comparative Analysis of the Mouse 1-Megabase Region Orthologous to the Human 11p15 Imprinted Domain

  • First Published November 1, 2000
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