Method
Read clouds uncover variation in complex regions of the human genome
- First Published August 18, 2015
Method
Discovery of recurrent structural variants in nasopharyngeal carcinoma
- First Published November 8, 2013
Research
The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes
- First Published March 11, 2013
Method
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements
- First Published September 5, 2012
Resource
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- First Published September 5, 2012
Method
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage
- First Published August 27, 2010
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Resource
ProPhylER: A curated online resource for protein function and structure based on evolutionary constraint analyses
- First Published October 21, 2009
Letter
Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention
- First Published August 24, 2009
LETTER
Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement
- First Published July 14, 2008
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
ARTICLE
De novo discovery of a tissue-specific gene regulatory module in a chordate
- First Published September 16, 2005
ARTICLE
Distribution and intensity of constraint in mammalian genomic sequence
- First Published June 17, 2005
Methods
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
- First Published June 17, 2005
LETTER
Transcript Level Alterations Reflect Gene Dosage Effects Across Multiple Tissues in a Mouse Model of Down Syndrome
- First Published July 1, 2004
RESOURCE
Integrated and Sequence-Ordered BAC- and YAC-Based Physical Maps for the Rat Genome
- First Published April 1, 2004
Methods
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
- First Published April 1, 2004
LETTER
The Genomic Sequence and Comparative Analysis of the Rat Major Histocompatibility Complex
- First Published April 1, 2004
LETTER
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
- First Published April 1, 2004
RESOURCE
Generation, Annotation, Evolutionary Analysis, and Database Integration of 20,000 Unique Sea Urchin EST Clusters
- First Published December 1, 2003
Methods
Clone-Based Systematic Haplotyping (CSH): A Procedure for Physical Haplotyping of Whole Genomes
- First Published December 1, 2003
ARTICLE
New Evidence for Genome-Wide Duplications at the Origin of Vertebrates Using an Amphioxus Gene Set and Completed Animal Genomes
- First Published June 1, 2003
LETTER
Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes
- First Published May 1, 2003
METHODS
LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA
- First Published March 12, 2003
METHODS
A Human cDNA Expression Library in Yeast Enriched for Open Reading Frames
- First Published September 20, 2001
LETTER
Partitioning of Tissue Expression Accompanies Multiple Duplications of the Na+/K+ ATPase α Subunit Gene
- First Published September 20, 2001
RESOURCE
An Oligonucleotide Fingerprint Normalized and Expressed Sequence Tag Characterized Zebrafish cDNA Library
- First Published August 16, 2001
RESOURCE
Panel of Microsatellite Markers for Whole-Genome Scans and Radiation Hybrid Mapping and a Mouse Family Tree
- First Published September 1, 1999
LETTER
A Contiguous 3-Mb Sequence-Ready Map in the S3–MX Region on 21q22.2 Based on High- Throughput Nonisotopic Library Screenings
- First Published April 1, 1999
RESEARCH
Estimation of Distances and Map Construction Using Radiation Hybrids
- First Published May 1, 1998
LETTER
Bacterial Contig Map of the 21q11 Region Associated with Alzheimer’s Disease and Abnormal Myelopoiesis in Down Syndrome
- First Published April 1, 1998