Method
Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data
- First Published May 24, 2022
Research
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding
- First Published August 10, 2018
Corrigendum
Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal
- First Published December 1, 2017
Research
Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha
- First Published April 6, 2017
Corrigendum
Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal
- First Published November 1, 2016
Method
Read clouds uncover variation in complex regions of the human genome
- First Published August 18, 2015
Research
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
- First Published May 29, 2015
Research
Genome accessibility is widely preserved and locally modulated during mitosis
- First Published November 4, 2014
Research
Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal
- First Published October 7, 2014
Research
Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape
- First Published June 24, 2014
Method
Discovery of recurrent structural variants in nasopharyngeal carcinoma
- First Published November 8, 2013
Research
DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types
- First Published May 8, 2013
Research
A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity
- First Published April 1, 2013
Research
Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions
- First Published March 12, 2013
Research
The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes
- First Published March 11, 2013
Resource
Dynamic DNA methylation across diverse human cell lines and tissues
- First Published January 16, 2013
Method
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements
- First Published September 5, 2012
Method
Predicting cell-type–specific gene expression from regions of open chromatin
- First Published September 5, 2012
Resource
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- First Published September 5, 2012
Research
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
- First Published February 2, 2012
Resource
High-resolution mapping of open chromatin in the rice genome
- First Published November 22, 2011
Research
Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells
- First Published November 16, 2011
Research
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration
- First Published July 27, 2011
Resource
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
- First Published July 12, 2011
Method
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells
- First Published November 24, 2010
Letter
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
- First Published January 12, 2010
Resource
ProPhylER: A curated online resource for protein function and structure based on evolutionary constraint analyses
- First Published October 21, 2009
Letter
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns
- First Published February 27, 2009
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
Methods
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)
- First Published December 12, 2005
ARTICLE
De novo discovery of a tissue-specific gene regulatory module in a chordate
- First Published September 16, 2005
ARTICLE
Distribution and intensity of constraint in mammalian genomic sequence
- First Published June 17, 2005
Methods
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
- First Published June 17, 2005
Methods
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
- First Published April 1, 2004
LETTER
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
- First Published April 1, 2004
LETTER
Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes
- First Published May 1, 2003
METHODS
LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA
- First Published March 12, 2003
LETTER
Partitioning of Tissue Expression Accompanies Multiple Duplications of the Na+/K+ ATPase α Subunit Gene
- First Published September 20, 2001