Searching journal content for articles similar to Szałaj et al. 26 (12): 1697.

Displaying results 1-7 of 7
For checked items
  1. ...and assigns gene program activity to individual cells or spatial locations. Through evaluation on both simulated and real biological data sets, DeCEP demonstrates complementary strengths over existing methods by enabling more fine-grained characterization of gene programs within specific contexts...
  2. ....ResultsQuantitative data-driven modeling of 3D chromosome organizationTo investigate chromatin motion in situations compatible with experiments, we first developed a data-driven polymer model to quantitatively describe the 3D chromatin organization. We modeled chromatin as a coarse-grained heteropolymer (Fig. 2A). Each...
  3. ...1 1 Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York 10029, USA; 2 Pacific Biosciences, Menlo Park, California 94025, USA; 3 Department of Computer Science and Engineering, University of Minnesota...
  4. ...visualization. The deep generative model has recently emerged as a powerful method for representation learning of single-cell genomics data (Ding et al. 2018; Lopez et al. 2018; Ding and Regev 2021; Liu et al. 2021). To integrate data sets from different batches to a joint embedding, we combine the strength...
  5. .... For the basal-like cluster, the regulome with the highest normalized enrichment score is SOX2, as well as MSC and HOXA9. Down-regulated regulomes include ZEB2, MYC, ESRRA, and KLF5 (Supplemental Fig. S2D).Assembly of a data-driven cell-shape regulatory networkTo integrate our data-driven GEMs with signaling...
  6. ...: Department of Biomedical Engineering, One Shields Ave, University of California, Davis, CA 95616, USA. ↵ 5 Corresponding author. E-MAIL DSmith@mednet.ucla.edu ; FAX (310) 825-6267. Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.204102...
  7. ...H, Khan Ossadtchi Alex Ossadtchi, A RM Leahy Simon V.M. Brown Simon, Yee Leahy 1549-5469 genome;GR-2290R 10.1101/gr.229002 1088-9051 Multiplex Three-Dimensional Brain Gene Expression Mapping in a Mouse Model of Parkinson's Disease Multiplex Three-Dimensional Brain Gene Expression Mapping in a Mouse...
For checked items

Preprint Server