Searching journal content for articles similar to Lenglez et al. 20 (9): 1250.

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  1. Research: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
    • Young Seok Ju,
    • Jose M.C. Tubio,
    • William Mifsud,
    • Beiyuan Fu,
    • Helen R. Davies,
    • Manasa Ramakrishna,
    • Yilong Li,
    • Lucy Yates,
    • Gunes Gundem,
    • Patrick S. Tarpey,
    • Sam Behjati,
    • Elli Papaemmanuil,
    • Sancha Martin,
    • Anthony Fullam,
    • Moritz Gerstung,
    • ICGC Prostate Cancer Working Group,
    • ICGC Bone Cancer Working Group,
    • ICGC Breast Cancer Working Group,
    • Jyoti Nangalia,
    • Anthony R. Green,
    • Carlos Caldas,
    • Åke Borg,
    • Andrew Tutt,
    • Ming Ta Michael Lee,
    • Laura J. van't Veer,
    • Benita K.T. Tan,
    • Samuel Aparicio,
    • Paul N. Span,
    • John W.M. Martens,
    • Stian Knappskog,
    • Anne Vincent-Salomon,
    • Anne-Lise Børresen-Dale,
    • Jórunn Erla Eyfjörd,
    • Ola Myklebost,
    • Adrienne M. Flanagan,
    • Christopher Foster,
    • David E. Neal,
    • Colin Cooper,
    • Rosalind Eeles,
    • G. Steven Bova,
    • Sunil R. Lakhani,
    • Christine Desmedt,
    • Gilles Thomas,
    • Andrea L. Richardson,
    • Colin A. Purdie,
    • Alastair M. Thompson,
    • Ultan McDermott,
    • Fengtang Yang,
    • Serena Nik-Zainal,
    • Peter J. Campbell,
    • and Michael R. Stratton
    Genome Res. June 2015 25: 814-824; Published in Advance May 11, 2015, doi:10.1101/gr.190470.115
    ....03 chromosomes slo tio (# of ts r M chr2 chr17 chr19 mtDNA chr4 chr13 mitophagy mitochondrial degradation escape of mtDNA nuclear membrane breaks down beginning of mitosis DNA double-strand breaks (chromosome shattering) and/or replication fork stalling mtDNA migration to the nucleus (micronucleus) (rate> 2x10...
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  2. Research: Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots
    • Loris Mularoni,
    • Yulian Zhou,
    • Tyson Bowen,
    • Sunil Gangadharan,
    • Sarah J. Wheelan,
    • and Jef D. Boeke
    Genome Res. April 2012 22: 693-703; Published in Advance January 4, 2012, doi:10.1101/gr.129460.111
    ...to characterize Ty1 integration. Surprisingly, some insertions were found in mitochondrial DNA sequences, presumably reflecting insertion into mitochondrial DNA segments that had migrated to the nucleus. The overwhelming majority of insertions were associated with the 5′ regions of Pol III transcribed genes...
  3. Method: Mapping genomic hotspots of DNA damage by a single-strand-DNA-compatible and strand-specific ChIP-seq method
    • Zhi-Xiong Zhou,
    • Mei-Jun Zhang,
    • Xu Peng,
    • Yuko Takayama,
    • Xing-Ya Xu,
    • Ling-Zhi Huang,
    • and Li-Lin Du
    Genome Res. April 2013 23: 705-715; Published in Advance December 17, 2012, doi:10.1101/gr.146357.112
    ...immunoprecipitation followed by sequencing (SPI-seq) to map genomic hotspots of DNA damage. We demonstrated this method with Rad52, a homologous recombination repair protein, which binds to ssDNA formed at DNA lesions. SPI-seq faithfully detected, in fission yeast, Rad52 enrichment at artificially induced double-strand...
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