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Conant and Wagner 13 (9): 2052
.
Displaying results 1-10 of
127
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Research
:
Pangenome analysis reveals families of ubiquitin-ligase adaptors as key genomic divergence drivers that lead to hybrid incompatibility
Dongying Xie
,
Pohao Ye
,
Yiming Ma
,
and
Zhongying Zhao
Genome Res.
March 2026
36
:
506
-
521
;
Published in Advance
February 17, 2026
,
doi:
10.1101/gr.280885.125
..., presumably via accelerated recombination during fbxn gene
duplication
, thereby reinforcing genetic
divergence
among populations and between species.An unusually conserved genomic region is identified surrounding Cni-neib-1Given the highly dynamic nature of fbxn genes across C. nigoni populations...
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Research
:
Plant genome evolution in the genus
Eucalyptus
is driven by structural rearrangements that promote sequence divergence
Scott Ferguson
,
Ashley Jones
,
Kevin Murray
,
Rose Andrew
,
Benjamin Schwessinger
,
and
Justin Borevitz
Genome Res.
April 2024
34
:
606
-
619
;
Published in Advance
April 8, 2024
,
doi:
10.1101/gr.277999.123
...driver of
divergence
. The loss of syntenic regions also contribute to
divergence
but at a slower pace than that of rearrangements. We hypothesize that
duplications
and translocations are potentially the greatest contributors to Eucalyptus
divergence
.Genomes from all kingdoms are highly organized but vary...
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Research
:
The evolution of duplicate gene expression in mammalian organs
Katerina Guschanski
,
Maria Warnefors
,
and
Henrik Kaessmann
Genome Res.
September 2017
27
:
1461
-
1474
;
Published in Advance
July 25, 2017
,
doi:
10.1101/gr.215566.116
...contributor to the phenotypic diversity of living organisms (Ohno 1970; Kaessmann 2010; Chen et al. 2013). It generates novel genomicmaterial that can bemolded through selective and neutral evolutionary processes. Upon
duplication
, one paralog may
diverge
in function, or both paralogs partition the ancestral...
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Method
:
Unveiling the functional fate of duplicated genes through expression profiling and structural analysis
Alex Warwick Vesztrocy
,
Natasha Glover
,
Paul D. Thomas
,
Christophe Dessimoz
,
and
Irene Julca
Genome Res.
October 2025
35
:
2273
-
2284
;
Published in Advance
August 14, 2025
,
doi:
10.1101/gr.280166.124
...correlate with
asymmetric
functional
divergence
. It is generally accepted that, following
duplication
, the two gene copies typically undergo a period of accelerated evolution (Huminiecki and Wolfe 2004), which may be apparent only in one copy (Huerta-Cepas et al. 2011; Pegueroles et al. 2013; Pich I Roselló...
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Research
:
The subgenomes show asymmetric expression of alleles in hybrid lineages of
Megalobrama amblycephala
×
Culter alburnus
Li Ren
,
Wuhui Li
,
Qinbo Qin
,
He Dai
,
Fengming Han
,
Jun Xiao
,
Xin Gao
,
Jialin Cui
,
Chang Wu
,
Xiaojing Yan
,
Guoliang Wang
,
Guiming Liu
,
Jia Liu
,
Jiaming Li
,
Zhong Wan
,
Conghui Yang
,
Chun Zhang
,
Min Tao
,
Jing Wang
,
Kaikun Luo
,
Shi Wang
,
Fangzhou Hu
,
Rurong Zhao
,
Xuming Li
,
Min Liu
,
Hongkun Zheng
,
Rong Zhou
,
Yuqin Shu
,
Yude Wang
,
Qinfeng Liu
,
Chenchen Tang
,
Wei Duan
,
and
Shaojun Liu
Genome Res.
November 2019
29
:
1805
-
1815
;
Published in Advance
October 24, 2019
,
doi:
10.1101/gr.249805.119
...allotetraploids, such as Brassica (Mason et al. 2011) and Triticum aestivum L. (Nelson et al. 1995), and a low frequency was detected in Ambystoma for pairing of
duplicated
premeiotic chromosomes instead of homologs (Neaves and Baumann 2011).With respect to
asymmetric
gene expression in the two hybrid lineages...
Abstract
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Research
:
Differential retention and divergent resolution of duplicate genes following whole-genome duplication
Casey L. McGrath
,
Jean-Francois Gout
,
Parul Johri
,
Thomas G. Doak
,
and
Michael Lynch
Genome Res.
October 2014
24
:
1665
-
1675
;
Published in Advance
August 1, 2014
,
doi:
10.1101/gr.173740.114
...Differential retention and
divergent
resolution of
duplicate
genes following whole-genome
duplication
Casey L. McGrath 1 , 3 , Jean-Francois Gout 1 , 3 , Parul Johri 1 , Thomas G. Doak 1 , 2 and Michael Lynch 1...
Abstract
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LETTER
:
cis
-Regulatory and Protein Evolution in Orthologous and Duplicate Genes
Cristian I. Castillo-Davis
,
Daniel L. Hartl
,
and
Guillaume Achaz
Genome Res.
August 2004
14
:
1530
-
1536
;
Published in Advance
July 15, 2004
,
doi:
10.1101/gr.2662504
...in Caenorhabditis elegans. Mol. Biol. Evol. 19 : 728 –735. ↵ The C. elegans Sequencing Consortium. 1998 . Genome sequence of the nematode C. elegans : A platform for investigating biology. Science 282 : 2012 –2018. ↵ Conant, G.C. and Wagner, A. 2003 .
Asymmetric
sequence
divergence
of
duplicate
genes. Genome Res...
Abstract
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Research
:
Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots
Loris Mularoni
,
Yulian Zhou
,
Tyson Bowen
,
Sunil Gangadharan
,
Sarah J. Wheelan
,
and
Jef D. Boeke
Genome Res.
April 2012
22
:
693
-
703
;
Published in Advance
January 4, 2012
,
doi:
10.1101/gr.129460.111
...Retrotransposon Ty1 integration targets specifically positioned
asymmetric
nucleosomal DNA segments in tRNA hotspots Loris Mularoni 1 , 6 , Yulian Zhou 2 , Tyson Bowen 2 , 7 , Sunil Gangadharan 3 , Sarah J. Wheelan 1 , 5 , 8...
Abstract
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Research
:
Cell-type- and chromosome-specific chromatin landscapes and DNA replication programs of
Drosophila
testis tumor stem cell–like cells
Jennifer A. Urban
,
Daniel Ringwalt
,
John M. Urban
,
Wingel Xue
,
Ryan Gleason
,
Keji Zhao
,
and
Xin Chen
Genome Res.
January 2026
36
:
83
-
101
;
Published in Advance
December 10, 2025
,
doi:
10.1101/gr.280809.125
...are defined by their ability to self-renew and differentiate into specialized cell types. During development and tissue homeostasis,
asymmetric
cell division of stem cells produces two genetically identical daughter cells that adopt distinct cell fates. It is hypothesized that
asymmetric
inheritance of cell...
Abstract
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LETTER
:
A burst of protein sequence evolution and a prolonged period of asymmetric evolution follow gene duplication in yeast
Devin R. Scannell
and
Kenneth H. Wolfe
Genome Res.
January 2008
18
:
137
-
147
;
Published in Advance
November 19, 2007
,
doi:
10.1101/gr.6341207
...-copy”) since the
divergence
of S. cerevisiae and S. bayanus Double-copy sequences evolve
asymmetrically
at the protein sequence level To examine the possibility of
asymmetric
rates of protein sequence evolution between members of
duplicated
pairs, we performed maximum-likelihood branch-length evaluation...
Abstract
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Single-cell gene signature scoring
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