High-Throughput Imaging of Brain Gene Expression

 

Follow up experiment.
Validation of the presented results via an independent experiment.


Figure 5.a : Comparison of the original and follow up experiment data.

Numeric output can be found in the file figure5.mat

Variable

 Description

meanR{1} (matrix, cell array element)

1977x1 normalized log-ratio average expression levels for  Normal brain

meanR{2} (matrix, cell array element)

1977x1 normalized log-ratio average expression levels for  AD  brain

diffs40 (vector)

List of the 40 most differentially expressed genes 

 

followupN (31x1 vector)

Vector of expression levels in the follow-up experiment in the Normal brain

followupA (31x1 vector)

Vector of expression levels in the follow-up experiment in the AD brain

C (scalar )

Correlation coefficient


 
 

Scatter plots of the gene expression differences.

Left plot   is the mean expression in the original experiment vs.
hippocampus in the follow up experiment. C = 0.65

Right plot is the hippocampal expression in the original experiment vs.
hippocampus  in the follow up  experiment.  C = 0.59
 











This Article

  1. doi: 10.1101/gr.204102 Genome Res. February 1, 2002 vol. 12 no. 2 244-254

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