The Nuclear Receptor Superfamily Has Undergone Extensive Proliferation and Diversification in Nematodes

Table 1.

C. elegans NR Genes Described in this Study

A. Identified by degenerate PCR screen
Chromosome Gene YACs Genome ORF cDNA (ESTs not sequenced) Comments
II nhr-41 Y42F9, Y27F6,  Y19D2, Y39E3
III nhr-6 Y68C4, Y43E9 C48D5.1 pBS/nhr6, (yk446a12) a.k.a. ceb-1 (Wilson et al. 1992);  cnr-8 (Kostrouch et al. 1995)
IV nhr-4 Y37F11, Y43F7,  Y49F10, Y39E2 F32B6.1 pBS/nhr4, (yk411a10)
nhr-5 Y73F8
nhr-7 Y72H7, Y51B3,  Y37G7 F54D1.4 yk396h7 cDNA splicing different from genome  ORF prediction
V nhr-18 Y54G1, Y5H2 F44C8.3a pBS/nhr18 upstream gene in potential operon
X nhr-3 Y52F5, Y52C11,  Y43C6 H01A20.b pBS/nhr3 cDNA splicing different from genome  ORF prediction
nhr-17 Y39F3, Y50C12,  Y40C3 C02B4.2
B. EST cDNA sequences completed
        Genome ORF ESTs Comments
II nhr-16 T12C9.1? CEESU44 cDNA splicing different from ORF prediction
nhr-21 F21D12.1 cm2h1, yk77h11 cDNAs reveal two isoforms
IV nhr-8 F33D4.1 cm14e12 cDNA splicing different from ORF prediction
nhr-11 ZC410.1 cm7a11 cDNA splicing different from ORF prediction
V nhr-13 cm9g2
nhr-15 F33E11.1 CEESV11
X nhr-14 T01B10.4 cm15g5 cDNA splicing different from ORF prediction
nhr-24/sex-1 F44A6.2 cm11f5 a.k.a.cnr-14 (Kostrouch et al. 1995)

This Article

  1. Genome Res. 9: 103-120

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