C. elegans NR gene structures defined by cDNA sequences. (Solid boxes) Coding; (open boxes) noncoding; (hatched boxes) DBD. Specific features of note (see text for additional discussion): (nhr-6) a marks site of possible alternate splice suggested by RT–PCR results. (nhr-7) vertical lines mark locations of AUG codons upstream of predicted initiation codon. Bracketb indicates possible splice sites that would remove upstream ORFs from the 5′ UTR. Also indicated is the site of a rare GC 5′ splice donor site (Blumenthal and Steward 1997). (nhr-11) bracket c marks predicted intron that would remove in-frame stop codon and extend the ORF. (nhr-16) bracket d indicates sequences without a current match in released genomic sequence. (nhr-21) e indicates the site of two splice acceptor sites separated by 6 bp; the 3′ site is used innhr-21a and the 5′ in nhr-21b.
