Extensive Conservation of Sex Chromosome Organization Between Cat and Human Revealed by Parallel Radiation Hybrid Mapping

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Figure 1.
Figure 1.

RH map of the domestic cat X chromosome and comparisons with human and mouse X chromosomes. Feline RH intermarker distances are expressed in centirays (cR5000), whereas human markers are labeled with their centiray positions on the RH framework (cR3000). Markers ordered with odds ≥1000:1 are underlined and in bold-face, whereas markers ordered with odds ≥100:1 are in boldface type only. Human loci positioned previously by our laboratory (Chen et al., in prep.) or for this study are labeled with an F (Frederick). In cases of multiple discordant human RH map positions reported in the database, a range of centiray positions is given. Because of the highly rearranged nature of the mouse X chromosome compared to human and cat, mouse X loci have been positioned adjacent to their respective cat homologs for clarity, with map positions (in cM) labeled next to the locus name.

This Article

  1. Genome Res. 9: 1223-1230

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