Figure 1.
Pericentromeric CAGGG repeats flanking a duplicated genic segment in 16p11.2 A schematic diagram summarizing the duplication of 26.5-kb genomic fragment from Xq28 to 16p11.2. The intron-exon structures of both the DXS1357E and the creatine transporter genes are depicted. Filled and open arrows indicate the position of SINE and LINE repetitive elements, respectively. The sequence of one of the paralogy boundaries within 16p11.2 as well as its proximity to the flanking 3.0-kb CAGGG repeat is shown. The data are based on a large-scale sequence comparison of cosmid subclones from 16p11.2 and Xq28 (Eichler et al. 1996).
