A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

Liliana Florea; George Hartzell; Zheng Zhang; Gerald M. Rubin; Webb Miller

doi:10.1101/gr.8.9.967

GENOME METHODS

A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

Published September 1, 1998. Vol 8 Issue 9, pp. 967-974. https://doi.org/10.1101/gr.8.9.967

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Abstract

We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.

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GENOME METHODS

A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

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