Alternate Polyadenylation in Human mRNAs: A Large-Scale Analysis by EST Clustering

Table 2.

Characteristics of the 1000 Largest Clusters

Clusters matching a GenBank primate sequence (%) Average no. of contigs per cluster ESTs assigned to internal priming (%) Clusters exhibiting poly(A) sites (no.)
2 3 4
72.7 1.6 13.9 159 27 3
  • With a BLAST score of 150 or higher.

  • ESTs are considered as originating from internal priming when followed in the contig by a stretch of 6 A’s or more, or by a 10 nucleotide sequence containing 7 A’s or more. Only ESTs that fully align with their corresponding contig (see Methods for details) are considered.

This Article

  1. Genome Res. 8: 524-530

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