Estimation of Distances and Map Construction Using Radiation Hybrids

Table 1.

Resolution (Minimum Resolvable Distance) and Range [Maximum Distance That Can Be Determined with Some Confidence (Z > 3)] for Panels Differing in the Number of Hybrids

Number of hybrids (N) Resolution Range
AB Ab aB ab θ Z(θ) D(R) (Mb) AB Ab aB ab θ Z(θ) D(R) (Mb)
10 4 1 0 5 0.156 2.01 0.170 4 1 1 4 0.40 1.24 0.51
20 9 1 0 10 0.080 4.3 0.084 16 4 4 16 0.40 3.83 0.51
50 24 1 0 25 0.033 11.0 0.034 19 6 6 19 0.48 3.63 0.65
83 13 1 0 69 0.037 17.5 0.038 28 13 13 29 0.63 3.17 0.99
0.198 3.5
90 16 1 0 73 0.031 19.2 0.032 31 14 14 31 0.62 3.47 0.97
0.009 0.27
93 30 1 0 62 0.021 20.3 0.021 31 15 15 32 0.65 3.20 1.04
0.525 26
100 49 1 0 50 0.017 22.0 0.017 34 16 16 34 0.64 3.50 1.02
200 99 1 0 100 0.009 43.8 0.009 62 38 38 62 0.76 3.16 1.43
500 249 1 0 250 0.004 109.2 0.004 144 106 106 144 0.85 3.17 1.88
1000 499 1 0 500 0.002 217.9 0.002 277 223 223 277 0.89 3.20 2.23

  • ↵G3 panel: retention frequency = 0.16, 1 R ≅ 5.2 Mb.

  • ↵TNG4 panel: retention frequency = 0.18, 1 R ≅ 0.28 Mb.

  • ↵GB4 panel: retention frequency = 0.32, 1 R ≅ 25 Mb.

This Article

  1. Genome Res. 8: 493-508

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