Figure 2.
Multiple sequence comparison of Lag1Sc protein and its homologs. (A) Five-way comparison of the full sequence of Lag1Sc with Lac1Sc, Lag1Ce-1, Lag1Ce-2, and Lag1Hs is shown. Residues identical in >50% of the compared sequences are on a black background; similar residues, based on evolutionary conservation, are on a gray background. (B) The region spanning amino acids 246–297 (Lag1p coordinates) was defined as the Lag1p motif. The corresponding sequences in the homologs, including in addition human and dog TRAM, have been compared, as in A. The percent identity and similarity with respect to Lag1p is tabulated.
