Table 2.
The Summary of the Ortholog Groups Showing the Number of ATP-Binding Proteins, the Operon Structure, and Known Functions
| Ortholog group | Gram-negative bacteria | Gram-positive bacteria | Cyanobacteria | Archaea | Known functions (substrates) | ||||
| Eco | Hin | Hpy | Mge | Mpn | Syn | Mja | |||
| 1-1 | 12 | 5 | 1 | 2 | 2 | 7 | 1 | sn-glycerol-3-phosphate, maltose/ maltodextrin, putrescine/ spermidine, sulfate/thiosulfate, molybdate, thiamin | |
| 1-2 | 4 | 2 | 1 | 5 | 1 | glycine betaine/l-proline, taurine, nitrate | |||
| 1-3 | 1 | 1 | 1 | 2 | ? | ||||
| 1-4 | 1 | ? | |||||||
| 2 | 9 | 3 | 1 | 1 | d-ribose, d-galactose, d-xylose, l-arabinose | ||||
| 3-1 | 4 | 2 | 2 | 2 | 3 | 2 | 2 | involved in cell division? | |
| 3-2 | 1 | 1 | 1 | 2 | ? | ||||
| 3-3 | 6 | 2 | 1 | 1 | glutamate/asparate, glutamine, arginine, histidine | ||||
| 3-4 | 1 | phosphonate | |||||||
| 3-5 | 2 | 4 | 2 | branched-chain amino acids | |||||
| 3-6 | (1) | (1) | (1) | (1) | ? | ||||
| 3-7 | 1 | 1 | 1 | 1 | 3 | 1 | phosphate | ||
| 4-1 | 12 | 6 | 3 | 2 | 2 | 1 | (2) | oligopeptide, dipeptide, nickel | |
| 4-2 | (2) | ? | |||||||
| 5-1 | 4 | 2 | 1 | 1 | 1 | 1 | 2 | vitamin B12, ferrichrome, iron(III) dicitrate, ferric enterobactin | |
| 5-2 | 1 | 2 | 2 | manganese | |||||
| 5-3 | 1 | 4 | 4 | 2 | 2 | cobalt | |||
| 6 | 7 | 8 | 3 | 3 | 2 | 10 | multidrug resistance? | ||
| 7 | 3 | 1 | 1 | 5 | 1 | capsule polysaccharide export (ABC-2) | |||
| 8 | (4) | (4) | (1) | (2) | (1) | ? | |||
| 9 | (1) | (1) | (1) | ? | |||||
| 10 | 1 | 1 | heme export? | ||||||
| 11 | 3 | (ABC-2?) | |||||||
| 12 | (1) | ? | |||||||
| 13 | (1) | ? | |||||||
| Total | 78 | 42 | 18 | 16 | 17 | 54 | 17 | ||
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Most of the transporter genes form operon structures, as indicated by shaded cells. Numbers in parentheses represent functional classes that are apparently different from ABC transporters.
