A Radiation Hybrid Map of Human Chromosome 5 with Integration of Cytogenetic, Genetic, and Transcript Maps

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Figure 4.
Figure 4.

The short arm of human chromosome 5 RH map. A complete map is available as an on-line supplement at http://www.cshl.org/gr. Markers ordered with a maximum likelihood ratio of >1000:1, compared with the next best order, are in boldface type and the farthest to the left of the shaded vertical bar representing the chromosome. These are designated backbone markers in the text. Markers ordered with a maximum likelihood ratio of <1000:1, but >10:1, are in plain text and indented. These markers, combined with the backbone markers, form the framework map as designated in the text. Distances between framework markers in centiRays are indicated. Proportional positions of each marker are indicated on the vertical shaded bar. Natural deletion bin assignments for representative backbone markers are indicated on the extreme left-hand side and refer to the regions indicated in Fig.2. Asterisks indicate STSs derived from the end sequence of cosmids mapped previously by FISH. Their previously assigned cytogenetic localizations are indicated in brackets adjacent to the asterisks. EST markers have an uppercase E suffix, and genes are designated using Genome Database nomenclature. Markers to the right of the shaded vertical bar were localized by two-point analysis. Each marker name is in line with the proportional position of the framework marker to which it was maximally linked with the associated lod score and distance directly below in brackets (lod, cR). The vertical line immediately to the left of each marker represents the interval to which it has been mapped relative to the proportional positions of the framework markers. Markers with the same interval are grouped. Broken lines join regions meeting the criteria for inclusion in the interval (see text).

This Article

  1. Genome Res. 7: 897-909

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