
Figure 1.
Schematic representation of the new fragmentation vectors, linearized between the Alu and telomere (TEL) fragments. (CEN6) Centromere from yeast chromosome VI; (tk–neo) thymidine kinase promoter coupled to the neomycin gene conferring G418 resistance to mammalian cells. Relevant restriction sites are indicated. The open arrowheads within HIS3 and ADE2 boxes indicate the transcriptional direction.











