Ataxia-Telangiectasia Locus: Sequence Analysis of 184 kb of Human Genomic DNA Containing the Entire ATM Gene

Table 4.

Potential Promoter Elements Predicted by TSSG, TSSW, and PSII Algorithms

No. Score TSSG TATA Start Score TSSW TATA Start Score PSII TATA Start
F1 13.3 714 743  —
R1 8.1 10,359 10,342 8.7 10,393
F2 7.0 10,513 9.9 10,513
F3 6.7 14,699 14,739 9.3 14,699 14,739
R2 16.9 74,575 74,546  —
F4 60.5 75,512 75,542
R3 15.1 80,433 80,404  —
F5 13.4 90,302  —
R4 73.7 115,070 115,040
F6 9.7 132,369 132,399 9.8 132,369 132,399
F7 59.9 141,310 141,340
F8 10.0 144,768 144,810  —
R5 7.5 176,805 176,775 9.8 176,805 176,773
  • To limit the output of these programs to high-score predictions, the cutoff values were adjusted to 8, 9, and 55. Predictions with lower score values were reported only when the score value of this element exceeded the respective cutoff score in one of the other programs.

  • (F) Promoter oriented forward with respect to ATMtranscription; (R) reverse orientation.

This Article

  1. Genome Res. 7: 592-605

Preprint Server