Fine Localization of the Torsion Dystonia Gene (DYT1) on Human Chromosome 9q34: YAC Map and Linkage Disequilibrium

Table 2.

Linkage Disequilibrium Between 9q34 Markers and theDYT1 Gene in the AJ Population

Locus Associated allele Percent affected chromosomes Percent control chromosomes δ
D9S62a 2 90   (36/40) 5 (14/280) 0.894
D9S62b 8 90   (36/40) 11 (32/280) 0.887
D9S159 12 95   (38/40) 21 (60/280) 0.937
D9S2158 4 90   (36/40) 35 (98/280) 0.846
D9S2159 4 92.5 (37/40) 54 (150/280) 0.837
D9S2160 4 95   (38/40) 23 (65/280) 0.935
D9S63 16 92.5 (37/40) 11 (32/280) 0.916
D9S2162 4 92.5 (37/40) 31 (87/280) 0.891
ASS 12 82.5 (33/40) 10 (29/280) 0.806

  • ↵Disease-bearing chromosomes from unrelated AJ affecteds (in parentheses).

  • ↵Phased, unrelated chromosomes from AJ controls (in parentheses).

This Article

  1. Genome Res. 7: 483-494

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