A 1.1-Mb Transcript Map of the Hereditary Hemochromatosis Locus

Table 2.

Comparison of the Three Gene-Finding Methods Used to Construct the Hemochromatosis Region Transcript Map

Bacterial clone cDNA no. Homology DS Exon trap Sample sequencing
pc157c3 28 zinc finger 2 1 EST03556
pc157c3 30 nonhistone 1 none yv81d05 yvh07a10
pc157c3 46 ORF 1 yd88g11
pc157c3 20 BT none 3 none
p196e20 21 BTF1 4 5 yn01g05 yg23d08 yg57h09 yu15h03
p196e20 29 BTF3 2 9 ye26g03 yo65f06
p196e20 23 BTF4 4 6 yd17d06
pc45p21 44 BTF5 2 4 ys04h08
pc45p21 32 BTF2 7 3 yg78f10 yn01c05
b13e17 41 genomic? none 1 none
b132a2 43 genomic? none 3 none
b132a2 36 genomic? 1 none none
b132a2 37 histone 2A 3 none ym29g03 yh87a03
b132a2 24 MHC class 1 1 2 ye98g01
b132a2 39 genomic? none 4 none
pc75l14 27 Ro/SSA 3 4 none
b20h20 22B NPT1-like 1 7 yr42a05 yf09g06
b20h20 22E NPT1-like 2 5 none
b136i7 NPT1 NPT1 N/A 3 yp74c05

  • ↵Number of DS contigs found to align with each cDNA. The number of clones contained within a contig and length of the contig varied.

  • ↵Number of individual exons trapped for each cDNA. Each exon may have been trapped numerous times.

  • ↵EST trace identifier numbers.

This Article

  1. Genome Res. 7: 441-456

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