
The percentage gene frequencies (numbers on map) of α+thalassemia in Melanesia parallels the intensity of malaria transmission (endemicity). The malaria transmission intensity goes from most intense (holoendemic) to least intense (hypoendemic). (A) Australia; (PNG) Papua New Guinea; (SI) Solomon Islands; (NC) New Caledonia; (V) Vanuatu; (ES) Espiritu Santo—an island in Vanuatu where the study by Williams et al. (1996) was performed. Figure adapted with permission from Miller (1996).











