Revisiting models of enhancer–promoter communication in gene regulation

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Figure 2.
Figure 2.

Overview of the structural bridge and hub models. (A) The structural bridge model postulates a stereotyped bridge composed of protein–protein interactions between transcription-associated proteins (TAPs). (B) The hub model postulates a malleable hub filled with high local concentrations of TAPs. (Created in BioRender. Danko, C. [2025] https://www.biorender.com)

This Article

  1. Genome Res. 35: 1277-1286

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