Examining the dynamics of three-dimensional genome organization with multitask matrix factorization

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Figure 6.
Figure 6.

Human pluripotency-specific boundary elements. (A) Boundary scores of transcriptionally active HERV-H retrotransposon sites during each time point of cardiomyocyte differentiation. (B) The top HERV-H site based on its transcription level in day 0 pluripotent state (within somatic chromosomes) and the overlapping sigDBs identified by TGIF-DB. (C,D) ESRG, a HERV-H-containing DE gene, overlapping a sigDB in cardiomyocyte differentiation (C) and in H1 differentiated to endoderm (D).

This Article

  1. Published in Advance March 20, 2025, doi: 10.1101/gr.279930.124 Genome Res. 35: 1179-1193

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