Table 1.
Breed genotypes and allele frequencies of select candidate variants
| Variant | Breed | AFb | Refc | Hetd | Home |
|---|---|---|---|---|---|
| Chr 13: 47440160, A/C, PDGFRA, splice acceptor | Çatalburun | 0.5 | 0 | 3 | 0 |
| Chr 6: 42492671, C/A, CSF1, stop-gained | Chow Chow | 1 | 0 | 0 | 6 |
| Elo | 0.1 | 4 | 1 | 0 | |
| Chr 3: 91871030, AACAG/A, LCORL, frameshift varianta | Spanish Mastiff | 1 | 0 | 0 | 6 |
| Berger Picard | 0.77 | 0 | 5 | 6 | |
| Briard | 0.67 | 0 | 4 | 2 | |
| Petit Bleu de Gascogne | 0.58 | 1 | 3 | 2 | |
| Bluetick Coonhound | 0.5 | 0 | 2 | 0 | |
| Bracco Italiano | 0.5 | 3 | 0 | 3 | |
| Spinone Italiano | 0.43 | 2 | 4 | 1 | |
| Pyrenean Mastiff | 0.36 | 3 | 3 | 1 | |
| Leonberger | 0.32 | 9 | 8 | 2 | |
| Beauceron | 0.3 | 2 | 3 | 0 | |
| Mastiff | 0.28 | 5 | 3 | 1 | |
| German Hound | 0.25 | 3 | 3 | 0 | |
| Griffon Nivernais | 0.25 | 2 | 2 | 0 | |
| Ariege Pointer | 0.2 | 3 | 2 | 0 | |
| Karakachan | 0.2 | 3 | 2 | 0 | |
| Picardy Spaniel | 0.2 | 3 | 2 | 0 | |
| Chr 30: 32785671, ACT/A, ITGA11, frameshift varianta | Pug | 1 | 0 | 0 | 3 |
| Japanese Chin | 1 | 0 | 0 | 4 | |
| Pekingese | 1 | 0 | 0 | 4 | |
| Shih Tzu | 1 | 0 | 0 | 4 | |
| Tibetan Spaniel | 1 | 0 | 0 | 4 | |
| Boston Terrier | 1 | 0 | 0 | 6 | |
| French Bulldog | 1 | 0 | 0 | 6 | |
| Lhasa Apso | 1 | 0 | 0 | 6 | |
| Chihuahua | 0.36 | 4 | 1 | 2 | |
| Biewer Terrier | 0.3 | 2 | 3 | 0 | |
| Portuguese Podengo Pequeno | 0.25 | 1 | 1 | 0 | |
| Russian Tsvetnaya Bolonka | 0.25 | 3 | 3 | 0 | |
| Chesapeake Bay Retriever | 0.21 | 4 | 3 | 0 |
-
aOnly breeds with AF ≥ 0.2 are displayed.
-
bFrequncy of the alternative allele within the breed.
-
cNumber of individuals homozygous for the reference allele.
-
dNumber of individuals with heterozygous genotype.
-
eNumber of individuals homozygous for the alternate allele.
