Figure 3.
Identification of new LCORL variants associated with canine body size. (A) Mutations found in the long isoform of LCORL. Early termination of translation and loss of the DUF4553 domain caused by frameshift mutations is associated with larger dog size (>55 cm/>25 kg). (B) Manhattan plots at the LCORL locus showing association with breed standard height for three different variants in separate linkage groups. (C,D) Boxplots showing associations between homozygous LCORL size-associated genotypes and breed standard height.
