RAmbler resolves complex repeats in human Chromosomes 8, 19, and X

Table 3.

Assembly score results for nine different data sets of synthetic HiFi reads with coverage 30×, based on a repetitive region with a variable-length (up to ±5% per copy) repeat unit of length {15, 20, 25} kb, and P = {1/250, 1/500, 1/1000}

Synthetic data set Assembly score
Repeat unit size (kb) Number of copies P RAmbler hifiasm LJA HiCANU Verkko
15 5 1/250 0.493 0.357 0.327 0.239 0.251
1/500 0.993 0.545 0.658 0.165 0.204
1/1000 0.454 0.426 0.346 0.547 0.408
20 1/250 0.422 0.599 0.418 0.441 0.276
1/500 0.797 0.309 0.618 0.312 0.246
1/1000 0.896 0.213 0.395 0.206 0.294
25 1/250 0.637 0.486 0.636 0.227 0.354
1/500 0.773 0.173 0.970 0.254 0.471
1/1000 0.465 0.231 0.409 0.278 0.345
  • Numbers in bold indicate the best assembly score on each row.

This Article

  1. Genome Res. 35: 863-876

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